ArticleDiseases of the esophagus : official journal of the International Society for Diseases of the Esophagus2026
Postoperative pulmonary complications after esophagectomy: risk factors and prediction model.
Article in Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative pulmonary complications (PPCs) affect up to one-third of patients undergoing esophagectomy and remain a major contributor to postoperative morbidity. This study aimed to identify pre- and perioperative risk factors for PPCs and to develop a predictive model.
methodsThis retrospective cohort study included patients who underwent esophagectomy for esophageal or gastroesophageal junction cancer at Amsterdam UMC between 2013 and 2023. PPCs included pneumonia, pleural effusion, pneumothorax, atelectasis, respiratory failure, aspiration, acute respiratory distress syndrome, tracheobronchial fistula, and persistent air leakage. Univariable and multivariable logistic regression with backward selection were used to identify predictors. Model performance was assessed with the area under the receiver operating characteristic curve (AUC). Statistical significance was set at P < 0.05.
resultsAmong 960 patients, 254 (26.5%) developed at least one PPC. Independent predictors were smoking status (former: OR 1.45, 95% CI 1.03-2.06; current: OR 1.74, 95% CI 1.15-2.63), non-epidural analgesia (paravertebral: OR 1.50, 95% CI 1.03-2.17; other: OR 1.57, 95% CI 0.88-2.82), and cervical versus intrathoracic anastomosis (OR 1.64, 95% CI 1.17-2.29). Drain configuration also influenced the risk of PPC: one-sided double drains were protective (OR 0.48, 95% CI 0.25-0.91), whereas bilateral drains increased the risk (OR 2.60, 95% CI 1.38-4.87), compared with one-sided single drains. The model demonstrated modest discrimination after validation of AUC: 0.598.
conclusionSmoking, paravertebral analgesia, cervical anastomosis, and bilateral drains were independently associated with increased PPC risk. Although predictive performance was modest, these modifiable and structural factors inform perioperative management. Future models should incorporate intraoperative and physiological variables to improve risk stratification.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.