Evidence map›Paper›PMID 42011489›Full record

ArticleMaterials today. Bio2026

Inhalable engineered probiotic outer membrane vesicles co-expressing multiple mpox antigens induce potent specific systemic and mucosal immune responses.

Xinting Fu, Wei Wang, Han Duan, Lixia Gao, Zihui Wei, Yanqiu Wu, Jiamei Wang, Fei Ma, Yunlong Zhang, Yue Jia and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Xinting FuDepartment of Microbiology, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong, 510515, China.
Wei WangInstitute for Engineering Medicine, Kunming Medical University, Kunming, Yunnan, 650500, China.
Han DuanDepartment of Microbiology, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong, 510515, China.
Lixia GaoDepartment of Microbiology, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong, 510515, China.
Zihui WeiDepartment of Microbiology, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong, 510515, China.
Yanqiu WuSchool of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, Guangdong, 510515, China.
Jiamei WangInstitute for Engineering Medicine, Kunming Medical University, Kunming, Yunnan, 650500, China.
Fei MaNHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Yunlong ZhangDepartment of Critical Care Medicine & Department of Emergency, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China.
Yue JiaNHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Qin GuSchool of Inspection, Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Changting HeSchool of Inspection, Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Yongli WangInstitute for Engineering Medicine, Kunming Medical University, Kunming, Yunnan, 650500, China.
Xueting LiuSchool of Inspection, Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Duo JiangSchool of Inspection, Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Zihuan LiuSchool of Inspection, Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Weihao LiaoSchool of Inspection, Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Xiaomei MaSchool of Inspection, Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Shuyuan WangSchool of Inspection, Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Yang LuSchool of Inspection, Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Chenguang ShenBSL-3 Laboratory (Guangdong), Guangdong Provincial Key Laboratory of Tropical Disease Research, Ministry of Education Key Laboratory of Infectious Diseases Research in South China, School of Public Health, Southern Medical University, Guangzhou, China.
Bin LiSchool of Inspection, Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Yuhui LiaoSchool of Inspection, Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Weifeng MaDepartment of Microbiology, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), Guangzhou, Guangdong, 510515, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monkeypox virus (MPXV) is transmitted through respiratory mucosa and close contact, including sexual transmission, especially among men who have sex with men (MSM). Using bioengineering, we constructed an inhaled bacterial outer membrane vesicles (OMVs) vaccine, ABM@OMV, to block MPXV transmission. This nanovaccine consists of OMVs from Δ

Indexed as

Biomimetic nanoparticlesEngineered probiotic vesiclesMpoxMucosal immunityMultiple antigens

Identifiers

PMID42011489
PMCPMC13092063

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.