Evidence map›Paper›PMID 42011228›Full record

Trial reportDrug design, development and therapy2026

Effect of Esketamine on Postoperative Pain in Children Undergoing Plasma Tonsillectomy: A Double-Blind, Randomized Controlled Trial.

Qianlong Lu, Yuxi Zhang, Jinjuan Duan, Siqi Xu

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug design, development and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qianlong LuDepartment of Anesthesiology, Bengbu Medical University, Anqing Medical Centre of Anhui Medical University, Anqing Municipal Hospital, Anqing, Anhui, People's Republic of China.
Yuxi ZhangDepartment of Anesthesiology, Bengbu Medical University, Anqing Medical Centre of Anhui Medical University, Anqing Municipal Hospital, Anqing, Anhui, People's Republic of China.
Jinjuan DuanDepartment of Anesthesiology, Bengbu Medical University, Anqing Medical Centre of Anhui Medical University, Anqing Municipal Hospital, Anqing, Anhui, People's Republic of China.ORCID 0000-0002-7351-9861
Siqi XuDepartment of Anesthesiology, Bengbu Medical University, Anqing Medical Centre of Anhui Medical University, Anqing Municipal Hospital, Anqing, Anhui, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the effects of esketamine compared with fentanyl on postoperative pain, sedation, and hemodynamics in children undergoing tonsillectomy under general anesthesia with endotracheal intubation. Methods: This randomized, double-blind, controlled trial included 54 children scheduled for plasma tonsillectomy, randomly allocated into group E (esketamine 0.5 mg·kg Results: FLACC scores at 2, 8, and 24 hours were comparable between groups ( Conclusion: Esketamine showed no significant difference in pain scores but more stable intraoperative hemodynamics compared with fentanyl in pediatric tonsillectomy using plasma energy.

Indexed as

KetaminePostoperative PainTonsillectomyChildChild, PreschoolDouble-Blind MethodFemaleFentanylHumansMaleEsketamineFentanylKetamineesketaminepediatricplasma tonsillectomypostoperative pain

Identifiers

PMID42011228
PMCPMC13092243

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.