Evidence map›Paper›PMID 42011207›Full record

ArticleOphthalmology science2026

Lens Color and Macular Pigment Density after Cataract Surgery: A Randomized Clinical Trial.

Hiroki Tsujinaka, Keigo Saeki, Kenji Obayashi, Tomo Nishi, Tetsuo Ueda, Satoru Kase

Abstract read
In one paragraph

Article in Ophthalmology science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hiroki TsujinakaDepartment of Ophthalmology, Nara Medical University, Kashihara, 6348521, Nara, Japan.
Keigo SaekiDepartment of Epidemiology, Nara Medical University, Kashihara, 6348521, Nara, Japan.
Kenji ObayashiDepartment of Epidemiology, Nara Medical University, Kashihara, 6348521, Nara, Japan.
Tomo NishiDepartment of Ophthalmology, Nara Medical University, Kashihara, 6348521, Nara, Japan.
Tetsuo UedaDepartment of Ophthalmology, Nara Medical University, Kashihara, 6348521, Nara, Japan.
Satoru KaseDepartment of Ophthalmology, Nara Medical University, Kashihara, 6348521, Nara, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the relationship between macular pigment optical density (MPOD) and intraocular lens (IOL) color after cataract surgery. Design: A single-center subanalysis study of a randomized clinical trial (CLOCK-IOL color study). Participants: This study included patients who underwent cataract surgery at our hospital from July 1, 2014, to June 30, 2017, whose MPOD could be measured at least once after surgery. Interventions: Patients were randomly assigned in a 1:1 ratio to either the yellow-tinted lens (TL) or clear lens (CL) groups. Main Outcome Measures: The primary outcome was the time-averaged difference in MPOD over time between the CL and yellow TL groups, up to 3 years postoperatively. Results: Overall, 155 patients (79 and 76 in CL and TL groups, respectively) were analyzed. At 1 year postoperatively, MPOD was significantly higher in the CL group than in the TL group (0.63 vs. 0.44; Conclusions: The CL group was associated with higher MPOD levels than the TL group over 3 years after cataract surgery. This suggests a more complex interaction between tinted IOL and macular pigment than previously recognized, warranting further investigation. Financial Disclosures: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

Indexed as

CataractIntraocular lensMacular pigment optical densityRandomized clinical trialSurgery

Identifiers

PMID42011207
PMCPMC13092179

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.