Evidence map›Paper›PMID 42011176›Full record

ArticleiScience2026

Optically pumped magnetometers enhance neuroimaging performance-An EEG, OPM, and SQUID-MEG study.

Marion Brickwedde, Paul Anders, Peter Krüger, Tilmann Sander, Peter J Uhlhaas

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marion BrickweddePhysikalisch-Technische Bundesanstalt, Department for Biosignals, 10587 Berlin, Germany.
Paul AndersPhysikalisch-Technische Bundesanstalt, Department for Biosignals, 10587 Berlin, Germany.
Peter KrügerPhysikalisch-Technische Bundesanstalt, Department for Biosignals, 10587 Berlin, Germany.
Tilmann SanderPhysikalisch-Technische Bundesanstalt, Department for Biosignals, 10587 Berlin, Germany.
Peter J UhlhaasCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität Berlin and Berlin Institute of Health, Department of Child and Adolescent Psychiatry, 13353 Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Much of our understanding of how neural circuit activity relates to human behavior and cognition stems from non-invasive assessments of the central nervous system. Further progress on key questions, however, requires measurements with a higher signal-to-noise ratio (SNR). Here, we show that in an established 40 Hz auditory steady-state paradigm, optically pumped magnetometers (OPMs) significantly outperform not only electroencephalography (EEG) but also conventional magnetoencephalography (MEG) in SNR and inter-trial phase coherence (ITPC). SNRs of OPMs were increased by up to 205% compared to EEG and by up to 40% compared to conventional MEG. As few as 10-16 OPM sensors were sufficient to significantly outperform 56 EEG electrodes. To maximize the representation of evoked responses, we employed spatial filters, which greatly enhanced SNRs across measurement modalities. Our data provide evidence for the potential of OPMs to enhance non-invasive neuroimaging, paving the way for important advances in basic as well as translational neuroscience.

Indexed as

neurosciencesensory neurosciencetechniques in neuroscience

Identifiers

PMID42011176
PMCPMC13091735

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.