Evidence map›Paper›PMID 42011078›Full record

Trial reportPalliative medicine2026

Exploring engagement with a web-based self-directed psychoeducational program for advanced cancer patients and their caregivers (iFOCUS): A sub study analysis of the DIAdIC trial.

Ulrik Sørensen Schmidt, Romy Van Rickstal, Vincent Van Goethem, Evi Bakker, Monika Pilch, Michael Connolly, Paul D'Alton, Catherine Jordan, Philip J Larkin, Peter May and 8 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Palliative medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ulrik Sørensen SchmidtUCD School of Psychology, University College Dublin, Ireland.ORCID 0000-0003-3383-8136
Romy Van RickstalEnd-of-Life Care Research Group, Vrije Universitiet Brussel & Ghent University, Belgium.ORCID 0000-0003-1999-1767
Vincent Van GoethemEnd-of-Life Care Research Group, Vrije Universitiet Brussel & Ghent University, Belgium.ORCID 0000-0002-1937-6724
Evi BakkerDepartment of Public Health, Erasmus MC, University Medical Center Rotterdam, The Netherlands.ORCID 0000-0001-9012-4151
Monika PilchUCD School of Psychology, University College Dublin, Ireland.ORCID 0000-0002-0610-0593
Michael ConnollyUCD School of Nursing, Midwifery & Health Systems & Our Lady's Hospice and Care Services, Dublin, Ireland.ORCID 0000-0002-6602-1803
Paul D'AltonUCD School of Psychology, University College Dublin, Ireland.ORCID 0000-0003-1420-6248
Catherine JordanUCD School of Psychology, University College Dublin, Ireland.
Philip J LarkinPalliative and Supportive Care Service, Lausanne University Hospital & University of Lausanne, Switzerland.
Peter MayCentre for Health Policy & Management, Trinity College Dublin, Dublin, Ireland.ORCID 0000-0001-8501-6500
Katherine BristoweCicely Saunders Institute of Palliative Care, Policy & Rehabilitation, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, UK.ORCID 0000-0003-1809-217X
Silvia de LeoAzienda Unità Sanitaria Locale, IRCCS di Reggio Emilia, Italy.
Aline De VleminckEnd-of-life care research group, Vrije Universiteit Brussel (VUB) & Ghent University, Belgium.ORCID 0000-0002-3321-9311
Joachim CohenEnd-of-life care research group, Vrije Universiteit Brussel (VUB) & Ghent University, Belgium.ORCID 0000-0002-7224-9476
Laurel NorthouseSchool of Nursing, University of Michigan, USA.
Peter HudsonCentre for Palliative Care, St Vincent's & The University of Melbourne, Australia.ORCID 0000-0001-5891-8197
DIAdIC Author Group
Suzanne GuerinUCD School of Psychology, University College Dublin, Ireland.ORCID 0000-0002-6744-7590

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSupporting psychoeducational functioning for advanced cancer patients and informal caregivers (dyads) can be challenging. Self-managed digital interventions offer a possible cost-effective alternative but often face low engagement.

aimTo examine engagement with the iFOCUS intervention and to understand why it failed to improve the expected outcomes.

designiFOCUS, a four-session digital self-managed 12-week intervention for dyads, was tested in six European countries as part of a randomized controlled trial. However, it showed no effects on outcomes. Using process evaluation data with 121 dyads, measures of engagement were examined to identify how engagement predicts dropout and to identify associations with patient/caregiver characteristics, post-intervention outcomes, and patient/caregiver evaluation of the intervention.

resultsMeasures of engagement showed variation in associations with participant characteristics. Lower engagement with the intervention among dyads at the outset, was associated with greater odds of dropout and engagement with the intervention decreased as the dyads progressed. Patients' level of education and caregivers' baseline emotional function, self-efficacy, dyadic coping, and knowledge of cancer were associated with engagement. However, there was no consistent evidence that engagement was associated with outcomes or evaluation of the intervention. DISCUSSION: While we identified several associations between engagement and patient/caregiver characteristics, there were inconsistencies in the extent and nature of the associations, with more evidence that baseline characteristics impacted engagement, than evidence that engagement impacted on outcomes. However, using multiple measures of engagement did provide additional insights. A key recommendation from this study is the need for consideration of assessments of engagement for digital interventions.

Indexed as

CaregiversInternet-Based InterventionNeoplasmsPatient Education as TopicAdaptation, PsychologicalAdultAgedEuropeFemaleHumansInternetMaleMiddle Agedcancercaregiversinternet-based interventionintervention adherencepalliative careprocess evaluationrandomized controlled trialtelemedicine

Identifiers

PMID42011078
PMCPMC13136541

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.