ArticleJournal of Korean medical science2026
Severe Fever With Thrombocytopenia Syndrome in Korea: Assessing the Impact of Hospital Patient Volume on Care Quality and Policy Implications.
Article in Journal of Korean medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe case fatality rate of severe fever with thrombocytopenia syndrome (SFTS) in South Korea remains high. We aimed to assess whether hospital patient volume affects the quality of care and clinical outcomes, to provide policy-relevant insights for improving SFTS management.
methodsWe retrospectively analyzed all SFTS patients reported to the Korea Disease Control and Prevention Agency (KDCA) from 2016 to 2021. Detailed clinical variables were collected from patients treated at 28 participating hospitals. SFTS management was compared according to hospital patient volume. The infectious disease physicians at the study hospitals were surveyed about their unmet needs in SFTS care.
resultsA total of 1,328 SFTS patients from 163 hospitals were reported during the study period. Of these, 60.7% (99/163) treated fewer than one patient per year. The distribution of patients was uneven across the country, with the highest annual incidence of 1.91 cases per 100,000 population in Gangwon province. From 657 patients across 28 study hospitals, five high-volume hospitals were compared with 12 low-volume hospitals to evaluate differences between the two extremes of hospital volume. High-volume hospitals had a shorter median turn-around time for formal results compared to low-volume hospitals (4 days [interquartile range, IQR 2-6] vs. 7 days [IQR 4-13],
conclusionSFTS cases occurred sporadically and rarely across the country, and the level of clinical expertise in managing SFTS varied between hospitals depending on patient volume. However, the case fatality rate showed no significant difference. Regional centralization of SFTS patients may be helpful in terms of improving quality of care and facilitating clinical trials for experimental therapeutics.
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