Evidence map›Paper›PMID 42010876›Full record

ArticleOrganic letters2026

Red-Light Photoredox C-H Alkylation of Acceptor Heterocycles Enabled by Substoichiometric NADH.

Uxía Deus-Lorenzo, Riccardo Di Forti, Alejandro Cadranel, María Tomás-Gamasa, José Luis Mascareñas, Mauro Mato

Abstract read
In one paragraph

Article in Organic letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Uxía Deus-LorenzoCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS) and Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15705 Santiago de Compostela, Spain.
Riccardo Di FortiDepartment Chemie und Pharmazie, Physikalische Chemie I, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Egerlandstraße 3, 91058 Erlangen, Germany.
Alejandro CadranelDepartment Chemie und Pharmazie, Physikalische Chemie I, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Egerlandstraße 3, 91058 Erlangen, Germany.ORCID 0000-0002-6597-4397
María Tomás-GamasaCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS) and Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15705 Santiago de Compostela, Spain.
José Luis MascareñasCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS) and Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15705 Santiago de Compostela, Spain.ORCID 0000-0002-7789-700X
Mauro MatoCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS) and Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15705 Santiago de Compostela, Spain.ORCID 0000-0002-2931-5060

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NADH is a key redox mediator in biology and biocatalysis, yet its catalytic use in non-enzymatic synthetic chemistry remains largely unexplored. Here, we show that NADH can act as a substoichiometric reductive quencher in red-light photoredox catalysis, enabling a redox-neutral C(sp

Indexed as

Heterocyclic CompoundsNADAlkylationCatalysisLightMolecular StructureOxidation-ReductionPhotochemical ProcessesRed LightHeterocyclic CompoundsNAD

Identifiers

PMID42010876
PMCPMC13140127

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.