ArticleJournal of integrative plant biology2026
The IKU2/RLK7-MAPK-MINI3 signaling module controls endosperm cellularization timing to determine seed size in Arabidopsis.
Article in Journal of integrative plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- The IKU2/RLK7-MAPK-MINI3 signaling module controls endosperm cellularization timing to determine seed size in Arabidopsis.Journal of integrative plant biology · 2026Article
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9 authors.
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Abstract
Seed size is a critical factor in determining crop yield. Recent studies highlighted the importance of the MPK3/MPK6 cascade in regulating seed size in both Arabidopsis and rice. However, the underlying mechanism is not fully elucidated. Here, we report a novel function for the MKK4/MKK5-MPK3/MPK6 module in controlling the timing of endosperm cellularization, thereby regulating the seed size. Loss of function of MKK4/MKK5 or MPK3/MPK6 results in precocious endosperm cellularization and smaller seeds. WRKY transcription factor WRKY10/MINI3 is identified as a substrate of MPK3/MPK6 in this process. During early silique development, MINI3 is expressed and undergoes phosphorylation, a process mediated by MPK3/MPK6 at five specific serine residues. The phospho-deficient MINI3
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