Evidence map›Paper›PMID 42010591›Full record

ArticleBMC musculoskeletal disorders2026

A late bearing insert dislocation was associated with new-onset rheumatoid arthritis after unicompartmental knee arthroplasty: a rare case report.

Huan Liu, Bo Wu

Abstract readCase Reports
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Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

2 authors.

Huan LiuDepartment of Orthopaedics, The 960th Hospital of PLA, 25 shifan Road, Tianqiao District, Jinan, Shandong, 250031, China.
Bo WuDepartment of Orthopaedics, The 960th Hospital of PLA, 25 shifan Road, Tianqiao District, Jinan, Shandong, 250031, China. wubo578@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBearing dislocation is a unique complication of mobile-bearing unicompartmental knee arthroplasty (UKA), with diverse underlying mechanisms. This article reports a rare mechanism of bearing dislocation following mobile-bearing UKA, which was probably associated with the new-onset rheumatoid arthritis (RA) leading to anterior cruciate ligament (ACL) insufficiency—aiming to highlight this uncommon etiology and its implications for clinical practice. CASE PRESENTATION: A 53-year-old woman presented with acute right knee pain and restricted mobility one day prior to admission, who was treated by mobile-bearing UKA for anteromedial osteoarthritis two years ago. Radiographs revealed bearing dislocation in this patient. Laboratory evaluation revealed elevated inflammatory markers (CRP 71.59 mg/L, ESR 74 mm/h) and positive RA serology(anti-CCP 39.09 U/mL, RF 32.4 IU/mL). Periprosthetic joint infection was rigorously excluded through multiple methods. The patient responded well to short-term corticosteroids and underwent one-stage revision total knee arthroplasty. Intraoperatively, extensive chronic synovitis, bearing dislocation, and severe ACL erosion/laxity due to synovial proliferation were observed. Histopathology confirmed synovial hyperplasia with dense lymphoplasmacytic infiltration and lymphoid follicle formation. Following standardized anti-rheumatic therapy, the patient regained satisfactory knee function with normalized inflammatory markers at 12-month follow-up.

conclusionThis case highlights that in patients who was present with delayed pain and elevated inflammatory markers after UKA. Inflammatory joint diseases such as RA should be included in the differential diagnosis alongside infection. Appropriate serological screening and multidisciplinary collaboration with rheumatology are essential for optimal management. As a single case report, these findings are hypothesis-generating and warrant confirmation in larger studies.

Indexed as

Arthritis, RheumatoidArthroplasty, Replacement, KneeKnee DislocationKnee ProsthesisProsthesis FailureFemaleHumansMiddle AgedOsteoarthritis, KneeReoperationTreatment OutcomeBearing dislocationCase reportMobile-bearing unicompartmental knee arthroplastyRheumatoid arthritis

Identifiers

PMID42010591
PMCPMC13227779

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