Evidence map›Paper›PMID 42010391›Full record

ReviewArtificial organs2026

From Rescue to Risk: Challenges and Controversies in Pushing the Boundaries of Organ Utilization by Machine Perfusion.

Damiano Patrono, Rebecca Panconesi, Nicola De Stefano, Renato Romagnoli

Abstract readReview
In one paragraph

Review in Artificial organs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Damiano PatronoGeneral Surgery 2U-Liver Transplant Center, Department of Surgery and Transplantation, AOU Città Della Salute e Della Scienza di Torino, Turin, Italy.ORCID https://orcid.org/0000-0002-4096-4504
Rebecca PanconesiGeneral Surgery 2U-Liver Transplant Center, Department of Surgery and Transplantation, AOU Città Della Salute e Della Scienza di Torino, Turin, Italy.
Nicola De StefanoGeneral Surgery 2U-Liver Transplant Center, Department of Surgery and Transplantation, AOU Città Della Salute e Della Scienza di Torino, Turin, Italy.
Renato RomagnoliGeneral Surgery 2U-Liver Transplant Center, Department of Surgery and Transplantation, AOU Città Della Salute e Della Scienza di Torino, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ongoing shortage of donor livers has prompted the use of extended criteria donors (ECD) and the development of ex-situ machine perfusion (MP) to expand the transplantable organ pool. MP has transformed liver transplantation (LT) by improving preservation, enabling better logistics, and allowing real-time viability assessment that is, a process aimed at predicting liver function after transplantation based on MP parameters. Although viability assessment has been proposed to safely expand donor pool and improve LT outcomes, it remains inconsistent. This article will summarize currently available assessment protocols and recapitulate studies exploring emerging viability biomarkers, discussing the need for an operational definition of viability assessment and its implications for the design of future studies on the subject.

Indexed as

LiverLiver TransplantationOrgan PreservationPerfusionAnimalsHumansTissue DonorsTissue Survivalflavin mononucleotidelactateliver transplantationmachine perfusionorgan utilizationviability assessment

Identifiers

PMID42010391
PMCPMC13397152

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.