Evidence map›Paper›PMID 42009999›Full record

ReviewInflammopharmacology2026

Safety and efficacy of COVID-19 vaccines in pregnant and lactating women: a comprehensive review.

Sumel Ashique, Mohini Mondal, Md Sadique Hussain, Anas Islam, Mohd Tariq, Dinesh Kumar Chellappan, Sabina Yasmin, Tabarak Malik, Juberahamad Rajjak Attar, Md Yousuf Ansari

Abstract readReview
PubMed Publisher
In one paragraph

Review in Inflammopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sumel AshiqueDepartment of Pharmaceutical Technology, Bharat Technology, Uluberia, West Bengal, 711316, India.
Mohini MondalDepartment of Pharmaceutical Technology, Bharat Technology, Uluberia, West Bengal, 711316, India.
Md Sadique HussainUttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun, Uttarakhand, 248007, India.
Anas IslamFaculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, 226026, India.
Mohd TariqDepartment of Biotechnology, Graphic Era (Deemed to Be University), Dehradun, Uttarakhand, 248002, India.
Dinesh Kumar ChellappanDepartment of Life Sciences, School of Pharmacy, IMU University (Formerly International Medical University), Bukit Jalil, 57000, Kuala Lumpur, Malaysia.
Sabina YasminDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, 62529, Abha, Saudi Arabia.
Tabarak MalikDepartment of Biomedical Sciences, Institute of Health, Jimma University, 378, Jimma, Ethiopia.
Juberahamad Rajjak AttarDepartment of Anaesthesia and Operations, College of Applied Medical Sciences, King Khalid University, Khamis Mushait, Abha, Saudi Arabia.
Md Yousuf AnsariIbne Seena Pharmacy College, AMES Group of Institutions, Shahabad, Hardoi, Uttar Pradesh, 241124, India. yousufniper@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breastfeeding plays a critical role in providing essential nutrients and antibodies that enhance the health of new-borns and infants, supporting their immune systems and overall growth and development. Healthcare professionals, universally recommend breastfeeding for the first six months of an infant's life, in conjunction with an appropriate complementary diet. However, the COVID-19 pandemic has understandably raised concerns among lactating mothers and pregnant women regarding the risks of infection and vaccine safety. Therefore, it is essential to carefully evaluate the potential dangers of COVID-19 transmission within this vulnerable population especially when considering vaccination for pregnant and breastfeeding women. Encouragingly, the United States Food and Drug Administration has granted approval for the use of two COVID-19 vaccines namely, Pfizer-BioNTech COVID-19 and Moderna COVID-19 to contain the spread of the COVID-19 virus. Both vaccines have been approved for administration in pregnant and breastfeeding women, providing much-needed reassurance to those with concerns about vaccine safety. It is important to recognize that the benefits of vaccination for both the mother and the infant far outweigh the risks associated with COVID-19 infection. Therefore, lactating mothers should view vaccination as a vital measure to protect themselves and their infants from the virus. In addition to elaborating on the successes of safety and effectiveness, this review is unique that it also includes current and newly updated evidence published between 2020 and 2025, comprehensively discussing on several newer vaccine platforms together with recent viral variants. Furthermore, it synthesizes information on the transfer of transplacental and a breast-milk antibody that outlines a clear evidence-gap that may direct further research within pregnant and lactating populations.

Indexed as

COVID-19COVID-19 VaccinesLactationPregnancy Complications, InfectiousBreast FeedingFemaleHumansPregnancySARS-CoV-2VaccinationVaccine EfficacyCOVID-19 VaccinesCOVID-19ImmunogenicityLactationPregnancySafetyVaccines

Identifiers

PMID42009999

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.