Evidence map›Paper›PMID 42009925›Full record

ArticleAesthetic plastic surgery2026

ADM-Assisted Breast Reconstruction vs Micro-Polyurethane Foam-Covered Implants in the Prepectoral Space: A Monocentric Study.

Sergio Miranda, Luca Mazzocconi, Giulio Tarantino, Samuele Frassoni, Vincenzo Bagnardi, Gaia Ghiringhelli, Pietro Caldarella, Francesca De Lorenzi

Abstract readComparative Study
In one paragraph

Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sergio MirandaDepartment of Plastic and Reconstructive Surgery, European Institute of Oncology, IRCCS, Milan, Italy.
Luca MazzocconiDepartment of Plastic and Reconstructive Surgery, European Institute of Oncology, IRCCS, Milan, Italy.
Giulio TarantinoDepartment of Plastic and Reconstructive Surgery, European Institute of Oncology, IRCCS, Milan, Italy. giulio.tarantino01@icatt.it.ORCID http://orcid.org/0000-0001-9569-097X
Samuele FrassoniDepartment of Statistics and Quantitative Methods, University of Milano-Bicocca, Milan, Italy.
Vincenzo BagnardiDepartment of Statistics and Quantitative Methods, University of Milano-Bicocca, Milan, Italy.
Gaia GhiringhelliDepartment of Plastic and Reconstructive Surgery, European Institute of Oncology, IRCCS, Milan, Italy.
Pietro CaldarellaUniversity of Milan, Milan, Italy.
Francesca De LorenziDepartment of Plastic and Reconstructive Surgery, European Institute of Oncology, IRCCS, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrepectoral breast reconstruction using acellular dermal matrices (ADMs) or micro-polyurethane foam-covered breast implants have emerged as commonly used surgical techniques. Although the use of both ADMs and micro-polyurethane foam-covered implants in prepectoral breast reconstruction are widely described in literature, comparative data remains limited.

objectivesOur goal was to compare the short-term and medium-term clinical outcomes as well as the patient-reported outcomes in patients undergoing direct-to-implant (DTI) prepectoral breast reconstruction using ADM versus micro-polyurethane foam-covered implants.

methodsA retrospective matched cohort study was conducted on 64 patients (32 ADM-wrapped and 32 micro-polyurethane foam-covered breast implants). Patients were matched based on prior surgery, adjuvant radiotherapy, and implant volume. Demographic and oncological characteristics, surgical variables, short- and medium-term outcomes, and patient-reported outcomes were compared between the two groups.

resultsThe micro-polyurethane group had significantly older patients (median age 53 vs. 47 years; p = 0.036). Periprosthetic fluid collection (31% vs. 3%; p = 0.006) and need for percutaneous fluid aspiration (38% vs. 9%; p = 0.016) occurred significantly more often in the ADM group. The indication for further surgery was also higher with ADM (47% vs. 19%; p = 0.031). Patient satisfaction showed a non-significant trend favoring micro-polyurethane implants in satisfaction with outcome domain (mean: 89 vs. 82; p = 0.060).

conclusionsBoth ADM-assisted reconstructions and micro-polyurethane implants demonstrated high performance in the short and medium term, and they were associated to high patient satisfaction with reconstruction. However, micro-polyurethane implants were associated with fewer periprosthetic fluid collections and a lower need for percutaneous fluid aspirations compared to the ADM group. These findings suggest a potential advantage in terms of reduced postoperative complications. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Acellular DermisBreast ImplantationBreast ImplantsBreast NeoplasmsMammaplastyPolyurethanesAdultCohort StudiesEstheticsFemaleFollow-Up StudiesHumansMastectomyMiddle AgedPatient Reported Outcome MeasuresPatient Satisfactionpolyurethane foamPolyurethanesADMBreast cancerDirect-to-implant (DTI)Micro-polyurethane foam-coated implantsPrepectoral breast reconstruction

Identifiers

PMID42009925
PMCPMC13433585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.