Evidence map›Paper›PMID 42009655›Full record

ArticleNature communications2026

TENT5C extends Odf1 poly(A) tail to sustain sperm morphogenesis and fertility.

Marine Baptissart, Ankit Gupta, Maira L Perez, Alexander C Poirot, Brian N Papas, Carlos M Guardia, Marcos Morgan

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Marine BaptissartMale Reproduction and RNA Biology Group, Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, NC, USA.ORCID http://orcid.org/0000-0001-6008-2851
Ankit GuptaMale Reproduction and RNA Biology Group, Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, NC, USA.
Maira L PerezPlacental Cell Biology Group, Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, NC, USA.ORCID http://orcid.org/0000-0002-1434-722X
Alexander C PoirotMale Reproduction and RNA Biology Group, Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, NC, USA.
Brian N PapasIntegrative Bioinformatics, Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, NC, USA.ORCID http://orcid.org/0000-0003-4540-1142
Carlos M GuardiaPlacental Cell Biology Group, Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, NC, USA.ORCID http://orcid.org/0000-0002-4662-9360
Marcos MorganMale Reproduction and RNA Biology Group, Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, NC, USA. marcos.morgan@nih.gov.ORCID http://orcid.org/0000-0002-3549-0375

Funding

Role of RNA modifications in spermatogenesis.ZIAES103339 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI MORGAN, MARCOS · 2019 to 2025
$10.8M
Autophagy and Intracellular Trafficking in Placental BiologyZIAES103370 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI GUARDIA, CARLOS · 2022 to 2025
$9.2M
Intramural NIH HHS ZIA ES103339U.S. Department of Health & Human Services | NIH | National Institute of Environmental Health Sciences (NIEHS) ZIAES103370
6 · The paper itself

Abstract

Changes in the poly(A) tail length of Odf1 and other transcripts critical for male fertility have been linked to translational activation during sperm formation

Indexed as

FertilityPoly APolynucleotide AdenylyltransferaseSpermatozoaAnimalsMaleMiceMorphogenesisRNA, MessengerSpermatidsSpermatogenesisPoly APolynucleotide AdenylyltransferaseRNA, Messenger

Identifiers

PMID42009655
PMCPMC13279820

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.