Evidence map›Paper›PMID 42009319›Full record

ArticleHospital pediatrics2026

Adherence With Diagnostic Stewardship Guidance and Sociodemographic Characteristics in the PICU.

Lauren D Booth, Matthew Linz, Christina Schumacher, Aaron M Milstone, David C Stockwell, Anna C Sick-Samuels

Abstract read
In one paragraph

Article in Hospital pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lauren D BoothDepartment of Anesthesia and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
Matthew LinzDepartment of General Surgery, Rutgers Health Robert Wood Johnson, School of Medicine, Newark, New Jersey.
Christina SchumacherDepartment of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland.
Aaron M MilstoneDepartment of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland.
David C StockwellDepartment of Anesthesia and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
Anna C Sick-SamuelsDepartment of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland.

Funding

Mentoring in prevention of hospital-acquired infections and antibiotic resistanceK24AI141580 · NIAID · JOHNS HOPKINS UNIVERSITY · PI AARON M MILSTONE · 2019 to 2026
$1.4M
Optimizing Respiratory Culture Practices for Mechanically Ventilated ChildrenK23HL161449 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Anna Sick-Samuels · 2022 to 2026
$992k
NHLBI NIH HHS K23 HL161449NIAID NIH HHS K24 AI141580
6 · The paper itself

Abstract

objectiveEvaluate the prevalence of bacterial cultures for patients with new-onset fever or instability obtained that were concordant with a new clinical decision support (CDS) tool within and across sociodemographic characteristics. PATIENTS AND

methodsA retrospective, cross-sectional evaluation assessing the prevalence of CDS-concordant cultures (blood, urine, respiratory cultures) obtained in an academic pediatric and pediatric cardiac intensive care unit 12 months before and after implementation of the new CDS tool. We compared CDS concordance before and after implementation within sociodemographic subgroups: race, ethnicity, primary language, payor type, biological sex, and age. Next, we compared CDS concordance across sociodemographic categories, before and after the intervention (eg, female vs male), using prevalence ratios (PRs).

resultsWe analyzed 2838 cultures (1503 pre and 1335 post). There was an improvement in CDS concordance in 13 of the 20 sociodemographic subgroups when comparing the postintervention with the preintervention period. Comparing across sociodemographic categories, there were no differences in CDS-concordant testing prevalence across race, ethnicity, primary language, or sex. However, we identified differences in CDS concordance by age. Before the intervention, cultures in patients younger than 6 months had 18% lower CDS concordance than patients older than 15 years (reference group) (PR 0.82, 95% CI 0.69-0.98); there was no difference after the intervention. Similarly, cultures in patients aged between >5 and 15 years had 23% lower CDS concordance than patients older than 15 years (PR 0.77, 95% CI 0.63-0.96); this attenuated after the intervention (PR 0.86, 95% CI 0.74-0.99).

conclusionsA new CDS tool was associated with an increase in CDS-concordant bacterial culture practices within most sociodemographic subgroups and enhanced culture ordering practices among younger patients.

Indexed as

Antimicrobial StewardshipBacterial InfectionsDecision Support Systems, ClinicalGuideline AdherenceIntensive Care Units, PediatricAdolescentChildChild, PreschoolCross-Sectional StudiesFemaleHumansInfantMaleRetrospective StudiesSociodemographic Factors

Identifiers

PMID42009319
PMCPMC13227609

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.