Evidence map›Paper›PMID 42007693›Full record

ArticleMicrobiology spectrum2026

Performance of the Xpert Xpress Strep A for detection of

Geneviève Amaral, Vijay J Gadkar, Abdulrahman Almodahka, David M Goldfarb, Ryan Penny, Nicole Watson, Suk Dhaliwal, Tammy Chen, Jocelyn A Srigley, Jonathan B Gubbay and 2 more

Abstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Establishment and clinical application of a rapid RPA-LFS assay for detectingFrontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Geneviève AmaralDepartment of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0009-0003-5697-2909
Vijay J GadkarDepartment of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-2676-3802
Abdulrahman AlmodahkaDepartment of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
David M GoldfarbDepartment of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0003-0835-9504
Ryan PennyDivision of Medical Microbiology, Virology and Infection Control, Department of Pathology and Laboratory Medicine, BC Children's and Women's Hospital and Health Centre, Vancouver, British Columbia, Canada.
Nicole WatsonDivision of Medical Microbiology, Virology and Infection Control, Department of Pathology and Laboratory Medicine, BC Children's and Women's Hospital and Health Centre, Vancouver, British Columbia, Canada.
Suk DhaliwalDivision of Medical Microbiology, Virology and Infection Control, Department of Pathology and Laboratory Medicine, BC Children's and Women's Hospital and Health Centre, Vancouver, British Columbia, Canada.
Tammy ChenDivision of Medical Microbiology, Virology and Infection Control, Department of Pathology and Laboratory Medicine, BC Children's and Women's Hospital and Health Centre, Vancouver, British Columbia, Canada.
Jocelyn A SrigleyDepartment of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-0030-7665
Jonathan B GubbayDepartment of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0003-0026-3786
Miguel ImperialDepartment of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-4061-7940
Lynne LiDepartment of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-1945-1173

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Canada, Group A streptococcal (GAS) pneumonia is a severe invasive GAS (iGAS) condition reportable to public health for consideration of chemoprophylaxis for close contacts. It is often complicated by parapneumonic effusion. Sterile site culture from pleural fluid is the diagnostic gold standard but is insensitive, particularly given that many patients will have received antibiotics prior to sample collection. Xpert Xpress Strep A (Cepheid, Sunnyvale, CA) is a quantitative real-time (qPCR) assay targeting the

Indexed as

Pleural EffusionReal-Time Polymerase Chain ReactionStreptococcal InfectionsStreptococcus pyogenesBacterial ProteinsChildChild, PreschoolExotoxinsFemaleHumansInfantLimit of DetectionMaleSensitivity and SpecificityBacterial Proteinserythrogenic toxinExotoxinseffusionempyemaGASGeneXpertparapneumonicpediatricpleural fluidStreptococcus pyogenesXpert

Identifiers

PMID42007693
PMCPMC13228042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.