Evidence map›Paper›PMID 42007688›Full record

ArticlemBio2026

Inhibitors of cytochrome

Deanna L Mendez, Pema L Childs, Amidala J Martinie, Jonathan Q Huynh, Andy F Zhu, Samuel R McKee, George S Ghabrial, Christina L Stallings, Robert G Kranz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Deanna L MendezDepartment of Biology, Washington University in St Louis, St. Louis, Missouri, USA.ORCID 0000-0002-0481-4816
Pema L ChildsDepartment of Biology, Washington University in St Louis, St. Louis, Missouri, USA.
Amidala J MartinieDepartment of Biology, Washington University in St Louis, St. Louis, Missouri, USA.
Jonathan Q HuynhDepartment of Biology, Washington University in St Louis, St. Louis, Missouri, USA.
Andy F ZhuDepartment of Biology, Washington University in St Louis, St. Louis, Missouri, USA.
Samuel R McKeeDepartment of Molecular Microbiology, Center for Women's Infectious Disease Research, Washington University School of Medicine, Saint Louis, Missouri, USA.
George S GhabrialDepartment of Molecular Microbiology, Center for Women's Infectious Disease Research, Washington University School of Medicine, Saint Louis, Missouri, USA.
Christina L StallingsDepartment of Molecular Microbiology, Center for Women's Infectious Disease Research, Washington University School of Medicine, Saint Louis, Missouri, USA.ORCID 0000-0002-2747-5618
Robert G KranzDepartment of Biology, Washington University in St Louis, St. Louis, Missouri, USA.ORCID 0000-0002-4309-9413

Funding

U.S. Department of Energy DE-SC0023727
6 · The paper itself

Abstract

The unique composition of bacterial electron transport chains (ETCs), distinct from the human mitochondrial ETC, presents opportunities for selective antibacterial targeting. Recently, inhibitors of bacterial ETCs have shown promise as potential antimicrobials, particularly against mycobacteria. Notably, bacterial cytochrome c (cyt

Indexed as

Anti-Bacterial AgentsBiosynthetic PathwaysCytochromes cEnzyme InhibitorsArtemisininsHumansAnti-Bacterial AgentsartemisininArtemisininsCytochromes cEnzyme Inhibitorscytochrome ccytochrome c assemblyhemeheme attachmentheme trafficking

Identifiers

PMID42007688
PMCPMC13170271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.