ArticleAdvances in Alzheimer's disease2025
Detecting Cognitive Impairment in African American Older Adults Using the LASSI-L and Plasma P-Tau
Article in Advances in Alzheimer's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Combining plasma biomarkers and cognitive challenge tests enhances prediction of functional trajectories of decline among older adults with cognitive impairment.Journal of Alzheimer's disease : JAD · 2026Article
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18 authors.
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Abstract
Background: Alzheimer's disease (AD) disproportionately affects Black/African American (B/AA) older adults, yet this group remains underrepresented in research. Traditional neuropsychological assessments, often developed on predominantly White populations, may not be reliable for B/AA individuals. The Loewenstein-Acevedo Scales for Semantic Interference and Learning (LASSI-L) have been shown to effectively differentiate individuals with amnestic mild cognitive impairment (aMCI) from cognitively unimpaired (CU) individuals. This study examines the relationship between LASSI-L performance and plasma p-tau Methods: Fifty-six older adults received clinical and cognitive evaluations and were deemed cognitively unimpaired (CU) and p-tau Results: After adjusting for age and MMSE score, the aMCI p-tau Conclusion: The study highlights the utility of the LASSI-L in conjunction with plasma biomarkers, particularly p-tau
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