ArticleMethodsX2026
Effect of tetrabenazine on Stroop interference in Huntington's disease: Protocol.
Article in MethodsX, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Tetrabenazine has been shown to improve gating of abnormal visual stimuli and improve postural stability in Huntington's disease (HD) patients as measured by computerized dynamic posturography testing. This open label pilot study aims to elucidate whether partial dopaminergic depletion via low dose tetrabenazine has a similar effect on masking out of abnormal visual stimuli on the Stroop interference test in HD patients. The study endpoint is the Golden formula calculated from off and on tetrabenazine Stroop test raw scores. Methods: The study will be performed as a single arm medication de novo or withdrawal trial. Informed consent to participate will be obtained from all participants and the next of kin. The data collection instrument is the standard Stroop color naming, word reading, and interference test.Stroop test will be administered in the morning to patients who are off tetrabenazine (de novo or three-day withdrawal). 12.5 mg of TBZ will be administered just after the first Stroop test and also 3 h later. On Stroop test will to be administered 6 h after the off Stroop test.The raw Stroop word reading, color naming, and interference scores will be recorded and used for further analysis using Golden's formula.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.