Evidence map›Paper›PMID 42007194›Full record

ArticleCJC open2026

Tricuspid Transcatheter-Edge-to-Edge-Repair and Transcatheter Tricuspid Valve Replacement for Tricuspid Regurgitation: Patient Profiles and Outcomes.

Julius Jelisejevas, Brian Chiang, Ali Husain, Gnalini Sathananthan, Robert Moss, Philipp Blanke, Jonathon A Leipsic, Janarthanan Sathananthan, Giacomo M Cioffi, Mario Togni and 6 more

Abstract read
In one paragraph

Article in CJC open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Julius JelisejevasCentre for Cardiovascular Innovation, St Paul's and Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Brian ChiangCentre for Cardiovascular Innovation, St Paul's and Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Ali HusainCentre for Cardiovascular Innovation, St Paul's and Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Gnalini SathananthanCentre for Cardiovascular Innovation, St Paul's and Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Robert MossCentre for Cardiovascular Innovation, St Paul's and Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Philipp BlankeCentre for Cardiovascular Innovation, St Paul's and Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Jonathon A LeipsicCentre for Cardiovascular Innovation, St Paul's and Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Janarthanan SathananthanCentre for Cardiovascular Innovation, St Paul's and Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Giacomo M CioffiDepartment of Cardiology, Fribourg University and Hospital, Fribourg, Switzerland.
Mario TogniDepartment of Cardiology, Fribourg University and Hospital, Fribourg, Switzerland.
Stéphane CookDepartment of Cardiology, Fribourg University and Hospital, Fribourg, Switzerland.
D Scott LimCentre for Cardiovascular Innovation, St Paul's and Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Anson CheungCentre for Cardiovascular Innovation, St Paul's and Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
John G WebbCentre for Cardiovascular Innovation, St Paul's and Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
David A WoodCentre for Cardiovascular Innovation, St Paul's and Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Robert H BooneCentre for Cardiovascular Innovation, St Paul's and Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Transcatheter tricuspid valve replacement (TTVR) is typically reserved for patients in whom tricuspid valve transcatheter edge-to-edge repair (T-TEER) is deemed unsuitable or unlikely to provide effective treatment. Comparative data evaluating patient profiles, disease stage, and outcomes between T-TEER and TTVR are limited. We aimed to analyze and compare patient profiles, selection, and outcomes with either T-TEER or TTVR. Methods: A total of 43 consecutive patients from May 2018 to April 2023 were retrospectively divided into 2 groups: Group-1 underwent T-TEER; and Group-2 underwent TTVR. Primary endpoints are as follows: inpatient mortality; and 30-day and 12-month mortality. Secondary endpoints are as follows: echocardiographic tricuspid regurgitationgrading; new pacemaker implantation; and heart failure-related readmissions at 30 days and 12 months. Results: A total of 43 patients underwent intervention (T-TEER, n = 14; TTVR, n = 29;). The mean age was 77.6 ± 10.3 years, and 38 patients (88%) were diagnosed with functional tricuspid regurgitation. The in-hospital mortality rate was 7%; the 30-day mortality rate was 12% with heart failure readmission for 14%.The 12-month mortality rate was 33%, with heart failure readmission for 37%. No in-hospital or 30-day mortality occurred in the T-TEER group. The 12-month mortality rate was 29% in the T-TEER group vs 34% in the TTVR group. The TTVR cohort showed numerically younger patients (76.2 ± 10.6 vs 80.4 ± 9.6 years, Conclusions: Our findings suggest that patients undergoing T-TEER vs TTVR may represent different disease stages. Further data are required to determine the best patient selection for T-TEER vs TTVR to optimize patient outcomes.

Indexed as

transcatheter tricuspid valve replacementTricuspid regurgitationtricuspid valve transcatheter edge-to-edge repair

Identifiers

PMID42007194
PMCPMC13084244

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.