Evidence map›Paper›PMID 42007125›Full record

ArticleAmerican journal of translational research2026

Jiangfu Fuwei granules alleviate chronic atrophic gastritis by suppressing angiogenesis through the PI3K-AKT-HIF1α pathway.

Yuqing Bi, Yanchun Chen, Jimei Jiang, Wangqi Mao, Xiao Zhang, Jiayi Liu, Xin Zhao, Yueqiu Dong, Yueqing Cai, Mei Li and 3 more

Abstract read
PubMed Full text at PMC Publisher
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Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yuqing BiDepartment of Pi-Wei Disease, The Third Affiliated Hospital of Yunnan University of Chinese Medicine Kunming 650500, Yunnan, China.
Yanchun ChenDepartment of Pi-Wei Disease, The Third Affiliated Hospital of Yunnan University of Chinese Medicine Kunming 650500, Yunnan, China.
Jimei JiangDepartment of Pi-Wei Disease, The Third Affiliated Hospital of Yunnan University of Chinese Medicine Kunming 650500, Yunnan, China.
Wangqi MaoDepartment of Pi-Wei Disease, The Third Affiliated Hospital of Yunnan University of Chinese Medicine Kunming 650500, Yunnan, China.
Xiao ZhangDepartment of Pi-Wei Disease, The Third Affiliated Hospital of Yunnan University of Chinese Medicine Kunming 650500, Yunnan, China.
Jiayi LiuDepartment of Pi-Wei Disease, The Third Affiliated Hospital of Yunnan University of Chinese Medicine Kunming 650500, Yunnan, China.
Xin ZhaoDepartment of Pi-Wei Disease, The First Affiliated Hospital of Yunnan University of Chinese Medicine Kunming 650021, Yunnan, China.
Yueqiu DongDepartment of Pi-Wei Disease, The Third Affiliated Hospital of Yunnan University of Chinese Medicine Kunming 650500, Yunnan, China.
Yueqing CaiDepartment of Pi-Wei Disease, The Third Affiliated Hospital of Yunnan University of Chinese Medicine Kunming 650500, Yunnan, China.
Mei LiDepartment of Oncology, The First Affiliated Hospital of Kunming Medical University Kunming 650118, Yunnan, China.
Xiang LiDepartment of Pi-Wei Disease, The First Affiliated Hospital of Yunnan University of Chinese Medicine Kunming 650021, Yunnan, China.
Yunpeng LuanDepartment of Pi-Wei Disease, The First Affiliated Hospital of Yunnan University of Chinese Medicine Kunming 650021, Yunnan, China.
Liyun JiangDepartment of Pi-Wei Disease, The Third Affiliated Hospital of Yunnan University of Chinese Medicine Kunming 650500, Yunnan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveJiangfu Fuwei granules (JFFW) are a widely used clinical prescription for the treatment of chronic atrophic gastritis (CAG), but the underlying molecular mechanism remains to be explored. This study aimed to elucidate the therapeutic mechanism of JFFW in alleviating CAG.

methodsA CAG mouse model was established using a combined approach, and the mice were treated with JFFW for six weeks. Network pharmacology was used to screen for active ingredients and signaling pathways. Subsequently,

results

conclusionThe therapeutic effect of JFFW on CAG is mainly achieved by inhibiting the PI3K-AKT-HIF1α signaling pathway, thereby suppressing abnormal angiogenesis and gastric inflammation.

Indexed as

angiogenesischronic atrophic gastritisJiangfu Fuwei granulesnetwork-based pharmacologyPI3K-AKT-HIF1α pathway

Identifiers

PMID42007125
PMCPMC13090885

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.