Evidence map›Paper›PMID 42007103›Full record

ArticleAmerican journal of translational research2026

Nursing-led stepwise pain-management protocol improves postoperative outcomes after hepatobiliary surgery.

Jing Wang, Zheng Wang, Pengyu Chen, Jinghua Liu, Li Li

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Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jing WangDepartment of Medical Imaging, Linyi People's Hospital Linyi 276000, Shandong, China.
Zheng WangDepartment of Hepatobiliary Surgery, Linyi People's Hospital Linyi 276000, Shandong, China.
Pengyu ChenDepartment of Hepatobiliary Surgery, Linyi People's Hospital Linyi 276000, Shandong, China.
Jinghua LiuDepartment of Hepatobiliary Surgery, Linyi People's Hospital Linyi 276000, Shandong, China.
Li LiDepartment of Hepatobiliary Surgery, Linyi People's Hospital Linyi 276000, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the impact of a stepwise pain-management protocol on postoperative recovery, pain control, complication rate, and resource utilization in patients undergoing hepatobiliary surgery.

methodsThis retrospective cohort study included 222 patients undergoing elective hepatobiliary surgery. Patients were assigned to a control group (n = 112) and an observation group (n = 110). The control group received routine care, while the observation group received a stepwise pain-management protocol. The primary outcome was postoperative pain intensity measured at different time points using the Numerical Rating Scale (NRS). Secondary outcomes included gastrointestinal recovery, complications, medical resource utilization, and quality of recovery, assessed using the QoR-40 questionnaire.

resultsThe stepwise pain-management protocol significantly improved perioperative outcomes. Patients in the observation group had lower NRS scores (including peak pain and activity-induced pain) at all postoperative time points (all P < 0.001). Gastrointestinal recovery was faster, and nausea scores were lower (P < 0.001). Hospital stay, ICU stay, nursing workload, and number of monitoring alarms were reduced (all P ≤ 0.001). Opioid consumption and patient-controlled analgesia usage decreased, while early mobilization ability, physical function, QoR-40 score, and safety all improved (all P < 0.001). Multivariate regression analysis confirmed that this regimen was an independent predictor of pain reduction (β = -2.155, P < 0.001).

conclusionThis study demonstrates that a series of pain management protocols can significantly improve postoperative outcomes in patients undergoing hepatobiliary surgery, reduce pain, shorten recovery time, and decrease complications.

Indexed as

clinical outcomesenhanced recoveryhepatobiliary surgerypostoperative careStepwise pain management

Identifiers

PMID42007103
PMCPMC13090875

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.