ArticleAmerican journal of translational research2026
Rapid fire needling combined with Xiaoliu Jin Jianwei decoction improves gastrointestinal symptoms and gastric mucosal lesions in chronic atrophic gastritis.
Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo investigate the efficacy of rapid-fire needling combined with Xiaoliu Jin Jianwei Decoction in chronic atrophic gastritis (CAG) and explore factors influencing the therapeutic effect.
methodsA total of 187 CAG patients admitted to our hsopital from April 2022 to April 2024 were divided into a control group (n=81, Xiaoliu Jin Jianwei Decoction alone) and an observation group (n=106, combined therapy), both receiving conventional drugs. After 4-weeks of treatment, GSRS score, total effective rate, gastric mucosal histopathology score and inflammatory factors were compared. Univariate and multivariate Logistic regression identified the influencing factors; a Nomogram model was constructed and verified by receiver operating characteristic (ROC) and calibration curves.
resultsThe observation group showed lower GSRS, histopathology scores, high-sensitivity C-reactive protein (hs-CRP) and tumor necrosis factor-α (TNF-α) levels, and higher total effective rate (93.40% vs 71.60%) than the control group (all P<0.05), with no difference in adverse reactions (P>0.05). GSRS score, histopathology score, hs-CRP, TNF-α and dietary habits were independent risk factors for poor efficacy. The Nomogram model had good predictive accuracy. Irregular diet was associated with higher GSRS, hs-CRP and TNF-α (P<0.05).
conclusionCombined therapy effectively improves gastrointestinal symptoms, reverses gastric mucosal lesions and enhances efficacy in CAG with good safety. The aforementioned indicators and dietary habits are key influencing factors.
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