Evidence map›Paper›PMID 42007085›Full record

ArticleData in brief2026

Lipidomic dataset of optic nerves from the silicone oil-induced ocular hypertension mouse model.

Zixuan Hao, Wenxuan Li, Isabella Moceri, Rui Ma, David Holden, Yuan Liu, Yu Hong, Sanjoy K Bhattacharya, Richard K Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zixuan HaoBascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA.
Wenxuan LiBascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA.
Isabella MoceriBascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA.
Rui MaBascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA.
David HoldenBascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA.
Yuan LiuBascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA.
Yu HongBascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA.
Sanjoy K BhattacharyaBascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA.
Richard K LeeBascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glaucoma is characterized by progressive degeneration of retinal ganglion cells and their optic-nerve axons, with elevated intraocular pressure (IOP) as a major risk factor for retinal ganglion cell death. Lipids are essential to axonal structure and signalling, yet optic nerve lipidomic datasets under high IOP are limited. We present a stage-specific lipidomic dataset from a mouse model of silicone oil (SO)-induced ocular hypertension (high IOP) with contralateral balanced salt solution (BSS)-injected controls. Optic nerves from high-IOP eyes and matched contralateral controls were harvested at 2 weeks and 8 weeks post-injection to represent early and established optic nerve degeneration, with

Indexed as

Axon degenerationLipidsOcular hypertensionOptic nerve

Identifiers

PMID42007085
PMCPMC13090666

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.