ArticleAmerican heart journal plus : cardiology research and practice2026
Elevated blood viscosity is associated with dysautonomia in long COVID symptoms.
Article in American heart journal plus : cardiology research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Long COVID is associated with elevated inflammatory and antibody levels. Elevated plasma proteins can increase blood viscosity and decrease blood flow. Our aim is to evaluate if blood viscosity is associated with long COVID outcomes. Methods: We conducted a cross-sectional study and included a sample of patients enrolled in our long COVID clinic. We estimated whole blood viscosity (WBV) using two previously validated formulas and compared it with the NASA lean test, COMPASS-31 scale as measures of dysautonomia and the symptom burden as measured by the modified COVID-19 Yorkshire scale. We obtained WBV at three different shear stress. We divided WBV and evaluated the distribution of symptom scores using univariate and multivariate models. Results: We included 185 patients for this study. Our sample had a mean age of 56 ± 11 years, included 53% minorities and 32% were women. The mean C19-YRSm did not change with increasing tertile of WBV ( Conclusion: Whole blood viscosity was associated with dysautonomia and not with long COVID symptoms.
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