Evidence map›Paper›PMID 42006996›Full record

ArticleCerebral circulation - cognition and behavior2026

Comment on "Relevance of cerebral microbleeds with leaky blood brain barrier in traumatic brain injury and protective role of interferon-gamma: A cohort study".

Sangameshwar Manikya, Varshini Vadhithala, Rajnish Kumar, Pankaj Nainwal

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Cerebral circulation - cognition and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sangameshwar ManikyaMalla Reddy Institute of Dental Sciences, Malla Reddy Vishwavidyapeeth (Deemed to be University), Suraram, Hyderabad, 500055, Telangana, India.
Varshini VadhithalaDr. D. Y. Patil Medical College Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed-to-be-University), Pimpri, Pune, 411018, Maharashtra, India.
Rajnish KumarNoida Institute of Engineering & Technology (Pharmacy Institute), Plot No.19, Knowledge Park-II, Greater Noida, 201306, India.
Pankaj NainwalFaculty of Pharmaceutical Sciences, Graphic Era Hill University, Dehradun, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

•Semi-quantitative Ktrans modeling may influence leaky CMB classification.•Absolute T1 mapping could improve BBB permeability accuracy.•Lesion location may outweigh lesion count for prognostic value.•Peripheral IFN-γ levels require longitudinal mechanistic validation.•Continuous BBB modeling may refine TBI biomarker stratification.

Indexed as

Blood–brain barrier permeabilityCerebral microbleedsDynamic contrast-enhanced MRIInterferon gammaTraumatic brain injury

Identifiers

PMID42006996
PMCPMC13091387

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.