Evidence map›Paper›PMID 42006925›Full record

ArticleBrain & spine2026

Postoperative adverse events after spinal surgery: Sex-specific risk profiles and ICU utilization.

Pavlina Lenga, Meltem Ivren, Gabriel Inci, Moritz Scherer, Philip Dao Trong, Maximillian Klass, Martin Dugas, Sandro M Krieg, Bogdana Suchorska

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Article in Brain & spine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Pavlina LengaDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Meltem IvrenDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Gabriel InciDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Moritz SchererDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Philip Dao TrongMedical Faculty of Heidelberg University, Heidelberg, Germany.
Maximillian KlassMedical Faculty of Heidelberg University, Heidelberg, Germany.
Martin DugasDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Sandro M KriegDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Bogdana SuchorskaDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sex differences in surgical outcomes are well-documented, yet data specific to spinal surgery remain conflicting. Research question: We investigated whether postoperative risk truly differs between sexes or if disparities reflect case mix and ICU triage practices. Methods: We analyzed prospectively collected data from 1337 spinal procedures (2023-2025) at a tertiary neurosurgical center. Multivariable logistic and Poisson regression models estimated the independent effect of sex on 30-day outcomes (complications, neurological deficits, rebleeding, ICU admission) and length of stay (LOS), adjusting for age, diagnosis, procedure type, comorbidities (AACCI), and operative time. Results: The cohort included 703 men and 634 women with similar baseline diagnoses. Thirty-day adverse events were equivalent between sexes, including aggregate complications (9.8% men vs 8.8% women), new neurological deficits (2.7% vs 2.1%), and adjusted LOS (mean 8.1 days). Conversely, ICU admission was significantly more frequent in men (8.0% vs 4.1%; p = 0.005). After adjustment, female sex was not associated with complications (aOR 0.95) or LOS, but remained independently associated with reduced ICU admission (aOR 0.42, 95% CI 0.24-0.73), even when accounting for comorbidities and operative time. Conclusions: Despite equivalent complication profiles and hospital stays, women were half as likely as men to be admitted to the ICU. Since this disparity persists after adjusting for clinical complexity and operative burden, ICU utilization in spinal surgery may be driven by provider practice patterns rather than objective physiological risk.

Indexed as

Intensive care unit (ICU)Postoperative adverse eventsSex differencesSpine surgeryTriage

Identifiers

PMID42006925
PMCPMC13087688

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.