ArticleFrontiers in medicine2026
Two-year clinical outcomes of standalone gonioscopy-assisted transluminal trabeculotomy in normal-tension glaucoma.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: To evaluate the 2-year efficacy and safety of gonioscopy-assisted transluminal trabeculotomy (GATT) for normal-tension glaucoma (NTG). Methods: This single-center retrospective case series included 9 NTG patients (12 eyes) undergoing GATT, with follow-up at postoperative day 1, week 1, and months 1, 3, 6, 12, 18, and 24. Primary outcomes were changes in intraocular pressure (IOP) and IOP-lowering medication burden at 24 months (counted by active ingredients). Complete and qualified success were assessed using strict criteria (from postoperative month 1 onward: IOP 6-15 mmHg and ≥20% reduction from baseline). Postoperative events and additional interventions/reoperations were recorded. Paired Results: The median age at surgery was 65 (53-70) years, and most eyes had moderate-to-advanced glaucoma. Mean IOP decreased from 17.33 ± 3.53 mmHg to 13.33 ± 2.35 mmHg at 24 months (mean reduction 4.00 ± 2.86 mmHg; 95% CI 2.18-5.82; Conclusion: GATT significantly reduced IOP and medication burden in NTG with a safety profile through 24 months. Larger prospective studies are warranted.
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