ArticleRSC advances2026
Integrated sonication-assisted deep eutectic solvent for extraction of antibacterial compounds from cacao shells.
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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8 authors.
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Abstract
The valorization of cacao shells offers high added value because of the rich content of bioactive compounds. This study investigated the application of cacao shell waste as an antibacterial agent through green extraction processes. The extraction was carried out by integrating SAE-DES (sonication-assisted and deep eutectic solvent) with a choline chloride-lactic acid-based solvent. The parameters of extraction, including temperature, solid-to-solvent ratio, and DES concentration, were optimized applying a Box-Behnken design in RSM (response surface methodology). The optimum conditions were found to be 80 °C, a solid-to-solvent ratio of 1 : 10, and a DES concentration of 62.65%, with TPC (total phenolic content) and TFC (total flavonoid content) of 4.94 ± 0.10 g GAE per g sample and 5.97 ± 0.09 g RE per g sample, respectively. Additionally, the mass transfer coefficient (
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