Evidence map›Paper›PMID 42006756›Full record

ArticleBMJ public health2026

TB-Free Chuuk: community-wide tuberculosis prevention and treatment with an integrated disease screening approach in Chuuk Lagoon, Federated States of Micronesia.

Stephanie Kern-Allely, Dorina Fred, Mayleen Dungawin, Thanumalaya Perumal Balathandan, Rupihner R Defang, Subhash Yadav, Praneel Maharaj, C Robert Horsburgh, E Jane Carter, Richard Brostrom

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Article in BMJ public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Stephanie Kern-AllelyPacific Island Health Officers Association, Honolulu, Hawaii, USA.ORCID https://orcid.org/0000-0001-9186-5090
Dorina FredChuuk State Department of Health Services, Chuuk, Micronesia (the Federated States of).
Mayleen DungawinChuuk State Department of Health Services, Chuuk, Micronesia (the Federated States of).
Thanumalaya Perumal BalathandanChuuk State Department of Health Services, Chuuk, Micronesia (the Federated States of).
Rupihner R DefangChuuk State Department of Health Services, Chuuk, Micronesia (the Federated States of).
Subhash YadavWestern Pacific Regional Tuberculosis Consultant, Suva, Fiji.
Praneel MaharajUnited Nations Development Programme, Suva, Fiji.
C Robert HorsburghDepartments of Global Health, Epidemiology, Biostatistics, and Medicine, Boston University Schools of Public Health and Medicine, Boston, Massachusetts, USA.
E Jane CarterThe Warren Alpert School of Medicine, Brown University, Providence, Rhode Island, USA.
Richard BrostromDivision of Tuberculosis Elimination, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Tuberculosis (TB) is a global public health threat and a leading cause of morbidity and mortality. To reduce long-term TB burden and address related diseases in Chuuk, Federated States of Micronesia, a community-wide campaign was conducted, incorporating an integrated approach to screening and treatment for TB disease, TB infection (TBI), Hansen's disease (HD) and diabetes. Here we present its design and initial outcomes. Methods: Public health workers administered tuberculin skin tests (TSTs) door-to-door among persons residing in areas of high TB incidence in the Chuuk Lagoon islands. Persons then attended a local screening site and were assessed for TB (TST measurement, verbal symptom review and chest x-ray, where indicated), HD (skin exam for rash or other cutaneous findings) and diabetes (haemoglobin A1c for adults). Persons diagnosed with either TB disease or TBI were offered treatment on-site. Persons with exam findings consistent with HD were referred for evaluation. Persons with a haemoglobin A1c of ≥6.5% were referred for follow-up. Results: During May-October 2023, 12 319 persons were screened through the community-wide campaign. An on-site panel of expert clinicians diagnosed 184 persons with TB disease and 2134 persons with TBI. Among those diagnosed with TB disease, 76.6% completed treatment. Among those diagnosed with TBI, 74.6% completed once-weekly rifapentine with isoniazid (3HP) treatment from community health workers. 17 new cases of HD and 395 new cases of diabetes were diagnosed. Conclusions: This cross-sectional analysis of the TB-Free Chuuk campaign demonstrated the success of community-wide screening to identify new cases of TB disease, TBI, HD and diabetes. Integrated screening provided the opportunity to address related public health priorities simultaneously, increasing the community's public health benefit. The development of local health worker capacity was key to achieving high treatment completion. Similar campaigns could be considered for other areas with high TB incidence with the goal of accelerating pathways to TB elimination.

Indexed as

Communicable Disease ControlCommunity HealthDisease Transmission, InfectiousMass ScreeningPublic Health

Identifiers

PMID42006756
PMCPMC13084875

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.