Evidence map›Paper›PMID 42006714›Full record

ReviewMaterials today. Bio2026

An overview of recent flexible- and soft-biomaterial applications in myocardial infarction and other cardiovascular diseases.

Andrea Roberto Calore, Veronica Torresan, Matteo Marchionni, Alessandro Gandin, Erica Basso, Diego Biasion, Stefano Mingoni, Alessia Molena, Gabriela Sartor, Giovanna Brusatin and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andrea Roberto CaloreUniversity of Padova, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, Padova, 35128, Italy.
Veronica TorresanUniversity of Padova, Department of Industrial Engineering, Padova, 35131, Italy.
Matteo MarchionniDepartment of Molecular Medicine, University of Padua School of Medicine, Padova, 35121, Italy.
Alessandro GandinUniversity of Padova, Department of Industrial Engineering, Padova, 35131, Italy.
Erica BassoUniversity of Padova, Department of Industrial Engineering, Padova, 35131, Italy.
Diego BiasionUniversity of Padova, Department of Industrial Engineering, Padova, 35131, Italy.
Stefano MingoniUniversity of Padova, Department of Industrial Engineering, Padova, 35131, Italy.
Alessia MolenaUniversity of Padova, Department of Industrial Engineering, Padova, 35131, Italy.
Gabriela SartorUniversity of Padova, Department of Industrial Engineering, Padova, 35131, Italy.
Giovanna BrusatinUniversity of Padova, Department of Industrial Engineering, Padova, 35131, Italy.
Vladimiro VidaUniversity of Padova, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, Padova, 35128, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases are currently the leading cause of mortality globally, with myocardial infarction representing one of the most prevalent and severe condition greater than even cancer. Current medical approaches are generally based on preventing and treating various post-infarction complications, failing to restore functional myocardial tissue. In this context, recent advances in the field of tissue engineering have been explored in an attempt to provide successful strategies for myocardial infarction repair, in addition to a multitude of other pathologies affecting the cardiovascular system. Biomaterials represent an essential component in developing innovative treatments such as tissue substitutes, drug/cell delivery vehicles, and prosthetic solutions, potentially avoiding invasive surgical procedures or, ultimately, transplantation. This review presents the various biomaterials that have found application in the last 10 years in the development of tissue engineering-based solutions for myocardial infarction repair. The discussion covers thermoplastic and elastomeric polymers, hydrogels, hybrid and smart material systems, and highlights their distinctive properties and the specific biological requirements they are able to meet. Additionally, recent applications in clinical trials are reviewed, describing their potential for clinical translation. This comprehensive overview aims to support researchers in selecting the most adequate biomaterial for myocardial infarction application.

Indexed as

CardiovascularClinical trialElastomericHybridMyocardial infarctionSmart materialsThermoplastic

Identifiers

PMID42006714
PMCPMC13091455

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.