Evidence map›Paper›PMID 42006706›Full record

ArticleMaterials today. Bio2026

Silicon doping-engineered asymmetric coordination and electronic structure modulation for amplified single-atom nanozyme catalytic therapy.

Bo Liu, Huihan Yi, Zhan Zhuang, Penghui Wei, Hongjia Zheng, Huimin Wang, Yifei Tu, Jinbao Xie, Yang Zhu, Xu Li

Abstract read
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bo LiuFujian Key Laboratory of Precision Medicine for Cancer, Department of Thoracic Surgery, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Huihan YiFujian Key Laboratory of Precision Medicine for Cancer, Department of Thoracic Surgery, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Zhan ZhuangFujian Key Laboratory of Precision Medicine for Cancer, Department of Thoracic Surgery, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Penghui WeiDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Hongjia ZhengDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Huimin WangDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Yifei TuFujian Key Laboratory of Precision Medicine for Cancer, Department of Thoracic Surgery, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Jinbao XieFujian Key Laboratory of Precision Medicine for Cancer, Department of Thoracic Surgery, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Yang ZhuDepartment of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Xu LiFujian Key Laboratory of Precision Medicine for Cancer, Department of Thoracic Surgery, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single-atom nanozymes (SANs), which feature tunable electronic structures and optimized atomic utilization efficiency, have garnered significant attention in biomedical applications. Despite substantial advancements, the catalytic performance of SANs remains suboptimal compared with that of natural enzymes, largely due to their symmetric coordination environments and electronic structures. Herein, we successfully engineer an asymmetrically coordinated Fe-based SAN with Si doping, termed Fe-SiN

Indexed as

Asymmetric coordinationCatalytic therapyFerroptosisHeteroatom-dopingSingle-atom nanozyme

Identifiers

PMID42006706
PMCPMC13090732

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.