Interplay between family history and polygenic risk for coronary heart disease: A cohort study among over 60 thousand individuals.

Carlos Iribarren, Meng Lu, Roberto Elosua, Martha Gulati, Nathan D Wong, Jamal S Rana

Abstract read

In one paragraph

Article in American journal of preventive cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carlos IribarrenKaiser Permanente Northern California Division of Research, Pleasanton, CA, USA.

Meng LuKaiser Permanente Northern California Division of Research, Pleasanton, CA, USA.

Roberto ElosuaCardiovascular Epidemiology and Genetics, Hospital del Mar Research Institute, Barcelona, Spain.

Martha GulatiDavis Women's Heart Center, Department of Cardiology, Houston Methodist DeBakey Heart & Vascular Center, Houston, TX, USA.

Nathan D WongHeart Disease Prevention Program, Mary and Steve Wen Cardiovascular Division, Department of Medicine, University of California Irvine, Irvine, CA, USA.

Jamal S RanaKaiser Permanente Northern California Division of Research, Pleasanton, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Family history of CADGeneticsPolygenic risk score

Identifiers

PMID42006428

DOI10.1016/j.ajpc.2026.101497

PMCPMC13084129

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.