ReviewVeterinary evidence
In dogs does the use of bone morphogenetic proteins with internal fixation accelerates fracture healing?
Review in Veterinary evidence. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PICO question: In dogs undergoing internal fracture fixation does the use of internal fixation and bone morphogenetic proteins (BMPs) accelerate healing compared to internal fixation alone? Clinical bottom line: Category of research: Treatment. Number and type of study designs reviewed: Zero. Strength of evidence: Zero. Outcomes reported: There is no evidence showing that dogs undergoing fracture fixation with any internal fixation method (e.g. locking plates, dynamic compression plates) and BMPs present accelerated healing compared to internal fixation alone. In view of the absence of this evidence, it is recommended that veterinarians should base their treatment choice on their experience in internal fixation methods and BMPs usage, their available materials for the methods, the cost, the potential adverse effects, and the case-specific factors. Therefore, veterinarians should acknowledge that both methods have potential risks and complications. Conclusion: In dogs undergoing fracture fixation, there is no statistical evidence to support fracture fixation with internal fixation and BMPs as a method that accelerates healing compared to internal fixation alone.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.