Evidence map›Paper›PMID 42006309›Full record

ArticleiScience2026

Arp2/3 involvement in intercellular bridge membrane fluctuations and constriction during neural stem cell divisions.

Bryce LaFoya, Michelle N Ortman, Adam Fries, Brad J Nolen, Kenneth E Prehoda

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Bryce LaFoyaInstitute of Molecular Biology, University of Oregon, Department of Chemistry and Biochemistry, 1229 University of Oregon, Eugene, OR 97403, USA.
Michelle N OrtmanInstitute of Molecular Biology, University of Oregon, Department of Chemistry and Biochemistry, 1229 University of Oregon, Eugene, OR 97403, USA.
Adam FriesGenomics and Cell Characterization Core, University of Oregon, 1229 University of Oregon, Eugene, OR 97403, USA.
Brad J NolenInstitute of Molecular Biology, University of Oregon, Department of Chemistry and Biochemistry, 1229 University of Oregon, Eugene, OR 97403, USA.
Kenneth E PrehodaInstitute of Molecular Biology, University of Oregon, Department of Chemistry and Biochemistry, 1229 University of Oregon, Eugene, OR 97403, USA.

Funding

Proliferative asymmetry in the neural stem cell lineage established by asymmetric cell divisionR00GM147601 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Bryce LaFoya · 2025 to 2026
$498k
Proliferative asymmetry in the neural stem cell lineage established by asymmetric cell divisionK99GM147601 · NIGMS · UNIVERSITY OF OREGON · PI LAFOYA, BRYCE · 2023 to 2024
$250k
NIGMS NIH HHS K99 GM147601NIGMS NIH HHS R00 GM147601
6 · The paper itself

Abstract

Near the end of animal cell division, the nascent sibling cells remain connected by an intercellular bridge (ICB). The ICB must undergo constriction or thinning before the final step of cytokinetic abscission can occur. The canonical ICB has a central midbody surrounded by flanking regions that are thinned by the migration of nascent siblings away from one another. We studied ICB thinning during the asymmetric divisions of neural stem cells (NSCs), which take place in the complex environment of the

Indexed as

Cell biologyMolecular biologyNeuroscience

Identifiers

PMID42006309
PMCPMC13087726

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.