Evidence map›Paper›PMID 42006215›Full record

ArticleKidney international reports2026

Randomized Clinical Trial on the Efficacy and Safety of Preoperative Enema in the Prevention of Peritoneal Dialysis Catheter Dysfunction.

Lijuan Zhao, Jin Zhao, Yan Xing, Ming Bai, Guoshuang Xu, Xiayin Li, Meilan Zhou, Yan Yu, Jun Yang, Shiren Sun

Abstract read
In one paragraph

Article in Kidney international reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lijuan ZhaoDepartment of Nephrology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Jin ZhaoDepartment of Nephrology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Yan XingDepartment of Nephrology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Ming BaiDepartment of Nephrology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Guoshuang XuDepartment of Nephrology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Xiayin LiDepartment of Nephrology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Meilan ZhouDepartment of Nephrology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Yan YuDepartment of Nephrology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Jun YangDepartment of Nephrology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Shiren SunDepartment of Nephrology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Current clinical practice guidelines do not universally recommend bowel preparation for peritoneal dialysis (PD) catheter insertion. This randomized controlled trial aimed to evaluate the efficacy and safety of preoperative enema in preventing PD catheter dysfunction. Methods: In this prospective, single-center trial, 136 patients undergoing PD catheterization were randomly assigned to receive either preoperative enema within 24 hours (enema group, Results: One hundred thirty-four participants completed the 6-month follow-up after excluding 2 patients (1 with scrotal leakage and 1 with acute kidney injury). Baseline characteristics showed no significant intergroup differences. The enema group demonstrated significantly lower incidence of catheter dysfunction requiring intervention at 3 months (10/68 [14.7%], unadjusted risk ratio (RR): 0.297, [95% confidence interval (CI): 0.129-0.682], Conclusion: Preoperative enema significantly reduces early PD catheter dysfunction risk without increasing complication rates. These findings support incorporating bowel preparation into standard preoperative protocols for PD catheter placement.

Indexed as

bowel preparationcatheter survival timeenema peritoneal dialysisperitoneal dialysis catheter dysfunction

Identifiers

PMID42006215
PMCPMC13088960

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.