ArticleFrontiers in cellular and infection microbiology2026
Whole-genome sequencing reveals the genomic characterization and evolution of carbapenem-resistant
Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Phylogenetic Relationships and Structural Conservation ofInternational journal of molecular sciences · 2026Article
- Antibiotic resistance, pathogenicity and genomic characteristics of a novel sequence type 6839Frontiers in cellular and infection microbiology · 2026Article
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6 authors.
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Abstract
Introduction: Methods: Thirty CRKP isolates collected from two tertiary hospitals (2023-2025) were tested for susceptibility to 15 antibiotics and subjected to whole-genome sequencing. Genome assembly and annotation employed standard pipelines, followed by multilocus sequence typing, capsular typing, phylogenetic reconstruction, pan-genome, and mobile genetic element analyses. Comparative genomic and statistical analyses were performed with publicly available data. Results: Most isolates originated from sputum (40%) and blood (23.3%) and were resistant to over 90% of β-lactam and carbapenem agents. Their genomes (5.2-5.8 Mb) contained on average 5,596 coding sequences. ST11 predominated (88.46%), mainly associated with KL25 (64.29%) and KL64 (17.86%) capsule types. The plasmid-borne Conclusions: The ST11-KL25 CRKP lineage shows enhanced adaptation and may become or is becoming the dominant clone in Gansu. These results highlight the necessity for continuous, longitudinal genomic surveillance to curb the spread of highly resistant
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