Evidence map›Paper›PMID 42006141›Full record

ArticleFrontiers in cellular and infection microbiology2026

Combined anti-PD-1 and amphotericin B therapy reduces fungal burden and enhances control of murine paracoccidioidomycosis.

Nycolas Willian Preite, Filipe Nogueira Franco, Bianca Vieira Dos Santos, Ana Claudia Soares Dos Santos, Coral Molist-Homs, Bruno Montanari Borges, Vera Lúcia Garcia Calich, Flavio Vieira Loures

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In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nycolas Willian PreiteInstitute of Science and Technology, Federal University of São Paulo, São José dos Campos, Brazil.
Filipe Nogueira FrancoInstitute of Science and Technology, Federal University of São Paulo, São José dos Campos, Brazil.
Bianca Vieira Dos SantosInstitute of Science and Technology, Federal University of São Paulo, São José dos Campos, Brazil.
Ana Claudia Soares Dos SantosInstitute of Science and Technology, Federal University of São Paulo, São José dos Campos, Brazil.
Coral Molist-HomsInstitute of Science and Technology, Federal University of São Paulo, São José dos Campos, Brazil.
Bruno Montanari BorgesDepartment of Biomedical Sciences and Pathobiology, Virginia Tech University, Blacksburg, VA, United States.
Vera Lúcia Garcia CalichDepartment of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.
Flavio Vieira LouresInstitute of Science and Technology, Federal University of São Paulo, São José dos Campos, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paracoccidioidomycosis (PCM) is a systemic fungal infection caused by

Indexed as

Amphotericin BAntifungal AgentsParacoccidioidesParacoccidioidomycosisProgrammed Cell Death 1 ReceptorAnimalsColony Count, MicrobialDisease Models, AnimalDrug Therapy, CombinationHost-Directed TherapyLungMiceMice, Inbred C57BLSurvival AnalysisTreatment OutcomeAmphotericin BAntifungal AgentsPdcd1 protein, mouseProgrammed Cell Death 1 Receptorcheckpoint blockadeimmunosuppressionimmunotherapyparacoccidioidomycosisPD-1

Identifiers

PMID42006141
PMCPMC13083198

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.