Evidence map›Paper›PMID 42006007›Full record

ArticleBioactive materials2026

Bioinspired "liquid-solid" biphasic dressing with exudate-gating transport, defense-attack antibacterial activity, and anti-adhesion property for exuding infected wound therapy.

Zizhao Chen, Changming Wang, Yixuan Li, Chunsheng Guan, Mingzhang Li, Hao Shen, Malcolm Xing, Botao Song, Jiang Chang

Abstract read
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In one paragraph

Article in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zizhao ChenKey Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi'an, 710069, China.
Changming WangDepartment of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai, 200233, China.
Yixuan LiKey Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi'an, 710069, China.
Chunsheng GuanKey Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi'an, 710069, China.
Mingzhang LiDepartment of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai, 200233, China.
Hao ShenDepartment of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai, 200233, China.
Malcolm XingDepartment of Mechanical Engineering, University of Manitoba, Winnipeg, MB, R3T 2N2, Canada.
Botao SongKey Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi'an, 710069, China.
Jiang ChangJoint Centre of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of heavily exuding infected wounds is complicated by excessive exudates, persistent bacterial colonization, and secondary trauma during dressing changes. Here, we develop a bioinspired "liquid-solid" biphasic dressing designed to address these challenges simultaneously. This dressing integrates a hylarana guentheri mucus-inspired medical antibacterial oil (guest phase) within a concave nanofiber membrane that mimics the structure of octopus suckers (host phase). This unique architecture enables an exudate-triggered self-adaptive gating mechanism, where the oil-filled concaves act as pressure-deformable gates. High hydrostatic pressure from excess exudate opens the gates for unidirectional transport, while low pressure maintains a closed state, thus dynamically regulating moisture and creating an optimal healing environment. The integrated oil, infused with thymol, establishes a synergistic "defend-and-attack" antibacterial barrier, preventing biofilm formation and neutralizing planktonic

Indexed as

Anti-adhesionDefense-attack antibacterialExuding infected woundsLiquid-solid biphaseSelf-adaptive gating transport

Identifiers

PMID42006007
PMCPMC13090611

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.