ArticleClinical, cosmetic and investigational dermatology2026
Double Chin Correction with Combination of High Intensity Focused Ultrasound and Hyaluronic Acid: A 24-Week Case Report.
Article in Clinical, cosmetic and investigational dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Submental fullness, commonly referred to as a double chin, is a frequent aesthetic concern influenced by subcutaneous fat accumulation and underlying skeletal structure. High-intensity focused ultrasound (HIFU) and hyaluronic acid (HA) filler injection have each been used as minimally invasive treatment options; however, reports on their combined use remain limited. We report two Asian female patients with mild to moderate submental fullness who were treated with a sequential combination of linear HIFU and HA filler injection in routine clinical practice. One patient underwent HIFU followed by HA injection, whereas the other received HA injection prior to HIFU treatment. Both patients demonstrated improvement in submental contour, cervicomental angle, and chin projection during follow-up, with results maintained at 24 weeks. Patient satisfaction was high, treatment-related discomfort was minimal, and no immediate or delayed adverse events were observed. Although limited by the small number of cases, these observations suggest that a combined approach using HIFU and HA filler may represent a well-tolerated, minimally invasive option for selected patients with submental fullness.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.