Evidence map›Paper›PMID 42005966›Full record

ArticleClinical parkinsonism & related disorders2026

Income, employment, and clinical outcomes in Parkinson's disease.

Melissa N Pacheco, Carmen Uribe, Jaeden Brown, Jacob D Jones

Abstract read
In one paragraph

Article in Clinical parkinsonism & related disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. What's in a name? reframing advanced Parkinson's disease as a multidimensional state.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Melissa N PachecoDepartment of Psychology, California State University San Bernardino, San Bernardino, CA, USA.
Carmen UribeDepartment of Psychology, California State University San Bernardino, San Bernardino, CA, USA.
Jaeden BrownDepartment of Psychology, California State University San Bernardino, San Bernardino, CA, USA.
Jacob D JonesDepartment of Psychology, California State University San Bernardino, San Bernardino, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Socioeconomic factors such as employment status and household income may influence clinical outcomes in Parkinson's disease, yet their associations with both motor and non-motor symptoms are not well characterized. This study examined whether employment status and income are associated with cognitive complaints, depressive symptoms, health-related quality of life, and motor severity among individuals with Parkinson's disease. Methods: Data were obtained from FoxInsight, and online longitudinal cohort study. Participants aged 40 years and older with Parkinson's disease who completed self-report questionnaires were included (n = 29,826). Multilevel models examined associations between employment status and household income with cognitive complaints, depressive symptoms, health-related quality of life, and motor severity across up to three annual assessments. Results: Employment status was significantly associated with all outcomes. Compared with full-time employment, unemployment and retirement were associated with more cognitive complaints, greater depressive symptoms, poorer health-related quality of life, and greater motor severity (all p < 0.05). Part-time employment was generally associated with fewer depressive symptoms and did not significantly differ from full-time employment on several outcomes. Lower household income was significantly associated with greater depressive symptoms, poorer health-related quality of life, and greater motor severity (all p < 0.05), but was not associated with cognitive complaints. Conclusion: Employment status and household income are important social determinants of both motor and non-motor outcomes in Parkinson's disease. These findings highlight the potential clinical relevance of socioeconomic factors shaping disease experience and emphasize the need for interventions that address economic and occupational vulnerability.

Identifiers

PMID42005966
PMCPMC13085081

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.