ArticlePrzeglad gastroenterologiczny2026
Global trend of organoid implementation for hepatocellular carcinoma research (2005-2024): bibliometric analysis.
Article in Przeglad gastroenterologiczny, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: In recent years, organoids have been increasingly used in the study of hepatocellular carcinoma (HCC). The purpose of this study is to analyse the research field of HCC organoids through bibliometrics, and to determine the key themes, trends, and contributions in this field. Aim: This study analyses global HCC organoid research trends from 2005 to 2024 to identify key developments and future directions. Material and methods: We screened literature on HCC and organoids from the Web of Science Core Collection (WOSCC) database from 2005 to 2024. CiteSpace and VOSviewer were used to visualise the bibliometric indicators. Results: The 267 articles analysed in this study came from 630 institutions in 40 countries/regions and were published in 149 journals. From 2005 to 2015, the number of publications continued to be low, and then entered a stage of rapid growth in 2016. The top three countries with the largest number of publications were China (128; 47.94%), the United States (65; 24.34%), and Germany (27; 10.11%). Conclusions: HCC organoid research has grown significantly, led by China, the United States, and Germany, focusing on model optimisation, molecular mechanisms, targeted therapy, and drug resistance, with emerging trends in long-term culture systems and patient-derived organoids.
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