Evidence map›Paper›PMID 42005942›Full record

ArticlePrzeglad gastroenterologiczny2026

The potential role of serum miR-182-5p and miR-127-5p in diagnosis of metabolic dysfunction-associated steatotic liver disease and its relationship with insulin resistance.

Tarek I Ahmed, Esraa A Mahmoud, Naglaa R Ismael, Omayma O Abdelaleem, Nada F Hemeda, Heba A El-Dash, Khalifa Abeer A, Ragab A Ali

Abstract read
In one paragraph

Article in Przeglad gastroenterologiczny, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tarek I AhmedDepartment of Internal Medicine, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Esraa A MahmoudDepartment of Zoology, Faculty of Science, Fayoum University, Fayoum, Egypt.
Naglaa R IsmaelDepartment of Zoology, Faculty of Science, Fayoum University, Fayoum, Egypt.
Omayma O AbdelaleemDepartment of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Nada F HemedaDepartment of Genetics, Faculty of Agriculture, Fayoum University, Fayoum, Egypt.
Heba A El-DashDepartment of Zoology, Faculty of Science, Fayoum University, Fayoum, Egypt.
Khalifa Abeer ADepartment of Physiology, Faculty of Medicine, Zagazig University, Egypt.
Ragab A AliDepartment of Internal Medicine, Faculty of Medicine, Fayoum University, Fayoum, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The most widespread chronic hepatic illness nowadays is metabolic dysfunction-associated steatotic liver disease (MASLD), which has a higher risk of several complications including progression to metabolic dysfunction-associated steatohepatitis (MASH), cirrhosis, and hepatocellular carcinoma (HCC). New clinical research has established that microRNAs (miRNAs) are causative factors in the progression of MASLD, which could be used as diagnostic biomarkers and help in producing new treatment modalities. Material and methods: Sixty adult patients with MASLD and 50 healthy individuals were incorporated in the current work. Serum miR-182-5p and miR-127-5p expression levels were measured using quantitative real-time polymerase chain reaction (RT-PCR). Results: Compared to healthy controls, patients with MASLD exhibited significantly downregulated serum levels of miR-182-5p and miR-127-5p ( Conclusions: miR-182-5p and miR-127-5p could serve as novel biomarkers for MASLD diagnosis and may offer a novel approach for the disease's therapy.

Indexed as

HOMA IRmetabolic dysfunction-associated steatotic liver diseasemiR-127-5pmiR-182-5p

Identifiers

PMID42005942
PMCPMC13085031

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.