Evidence map›Paper›PMID 42005858›Full record

ReviewPulmonary circulation2026

Schistosomiasis-Associated Pulmonary Arterial Hypertension in Brazil: A Call to Action for Enhanced Diagnostic Recognition-2025 Pulmonary Vascular Research Institute Infection in Pulmonary Vascular Disease Consortium Perspectives.

Camila M C Loureiro, Ricardo A Correa, Roberto José de Carvalho Filho, Brian B Graham, Ghazwan Butrous, Rudolf K F Oliveira

Abstract readReview
In one paragraph

Review in Pulmonary circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Camila M C LoureiroPulmonary Medicine, Santa Casa da Bahia Salvador Bahia Brazil.ORCID https://orcid.org/0009-0004-6231-5662
Ricardo A CorreaInternal Medicine/Pulmonary Division, Medical School Federal University of Minas Gerais Belo Horizonte Minas Gerais Brazil.ORCID https://orcid.org/0000-0003-1779-0443
Roberto José de Carvalho FilhoLaboratory of Applied Molecular Hepatology (LHeMA), Department of Medicine, Division of Gastroenterology Federal University of São Paulo São Paulo Brazil.
Brian B GrahamDepartment of Medicine University of California San Francisco San Francisco California USA.
Ghazwan ButrousCardiopulmonary Science University of Kent Canterbury Kent UK.ORCID https://orcid.org/0000-0002-6640-6332
Rudolf K F OliveiraDepartment of Medicine, Division of Respiratory Diseases Federal University of São Paulo São Paulo São Paulo Brazil.ORCID https://orcid.org/0000-0002-2252-8119

Funding

Role of Complement-Driven Pulmonary Vascular Inflammation in PHP01HL152961 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI STENMARK, KURT R. · 2020 to 2024
$14.1M
Investigating paclitaxel treatment in a pre-clinical model of Schistosoma-pulmonary hypertensionR01HL135872 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Brian Barkley Graham · 2017 to 2026
$5.1M
NHLBI NIH HHS P01 HL152961NHLBI NIH HHS R01 HL135872
6 · The paper itself

Abstract

Schistosomiasis-associated pulmonary arterial hypertension (Sch-PAH) is one of the most frequent etiologies of pulmonary arterial hypertension in Brazil and globally. The disease is a complication of hepatosplenic schistosomiasis characterized by portal hypertension, egg deposition, and granuloma formation in the pulmonary arteries leading to inflammation, vascular remodeling, increased pulmonary vascular resistance, and progressive right heart failure. During the Infection in Pulmonary Vascular Disease (iPVD) consortium meeting during the Pulmonary Vascular Research Institute (PVRI) annual meeting in January 2025, in Rio de Janeiro, Brazil, a dedicated symposium entitled schistosomiasis-associated pulmonary vascular disease in Latin America addressed the most relevant aspects of the epidemiology, diagnosis, and prevention of Sch-PAH in Brazil. This review summarizes the main discussed topics and serves as a call to increase efforts to understand the disease burden better and enhance diagnostic proficiency.

Indexed as

diagnosisepidemiologypulmonary arterial hypertensionschistosomiasis

Identifiers

PMID42005858
PMCPMC13084325

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.