ArticleGynecologic oncology reports2026
Surgical debulking with fertility preservation in primary extra-neural ependymoma presenting with widespread peritoneal and intra-abdominal disease: Case report and literature review.
Article in Gynecologic oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Extra-neural ependymoma is an extremely rare neoplasm with reported cases arising from the ovary, pelvis, broad and uterosacral ligaments, peritoneum and mediastinum. Case Presentation: A 29-year-old woman presented with abdominal pain. Computed tomography demonstrated bilateral adnexal masses, omental and peritoneal nodules and a 140 mm left upper quadrant mass. FDG PET/CT showed avid, disseminated abdominal disease. CA125 was 265. Differential diagnoses included tubo-ovarian malignancy, peritoneal carcinomatosis, and mesenchymal tumours. Diagnostic laparoscopy with biopsy established Stage IV extra-neural ependymoma based on histological features, immunophenotype and the absence of central nervous system disease on magnetic resonance imaging. She underwent primary cytoreduction including en bloc hysterectomy with ultra-low anterior resection, right salpingoophorectomy, left salpingectomy, peritonectomy, splenectomy with en-bloc partial resection of the left hemi-diaphragm and loop ileostomy. Intraoperatively, the right ovary was utilised for ex-vivo in-vitro oocyte maturation, and the left ovary was conserved for oocyte retrieval and cryopreservation for future surrogacy. Adjuvant chemotherapy was recommended but declined. She remained well at eleven months post-operatively. Conclusion: Extra-neural ependymomas are exceedingly rare with five reported cases of peritoneal ependymoma. Extra-neural ependymomas demonstrate distinct histological and immunophenotypic profiles including increased architectural variability within the spindled cell perivascular pseudorosettes characteristic of ependymomas and diffuse ER and PR positivity. Given limited evidence, optimal management remains undefined however surgical cytoreduction continues to be the cornerstone of management across reported cases with adjuvant treatment individualised. Certain fertility preservation strategies are concurrently feasible within a multidisciplinary framework and should be considered given reported cases are predominantly seen in younger females.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.