Evidence map›Paper›PMID 42005584›Full record

ArticleJournal of pain research2026

Analgesic and Sedative Effects of Virtual Reality on Children with Acute Pulpitis: A Study Protocol for a Randomised Controlled Trial.

Wenjuan Cao, Chunpeng Liu, Zaiyong Yang, Yuchen Wang, Jiayi Dou, Xueling Qiu, Liting Zhang, Aiqin Lv, Lu Tang

Abstract read
In one paragraph

Article in Journal of pain research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenjuan Cao *School of Nursing, Shandong Second Medical University, Weifang, Shandong, People's Republic of China.
Chunpeng Liu *Department of Stomatology, 960th Hospital of the Chinese People's Liberation Army, Jinan, Shandong, People's Republic of China.
Zaiyong Yang *Oral Medicine Teaching and Research Office, War Rescue Medical Department, Non-Commissioned Officer School, Army Medical University, Shijiazhuang, Hebei, People's Republic of China.
Yuchen WangDepartment of Stomatology, 960th Hospital of the Chinese People's Liberation Army, Jinan, Shandong, People's Republic of China.
Jiayi DouSchool of Nursing, Shandong Second Medical University, Weifang, Shandong, People's Republic of China.
Xueling QiuDepartment of Stomatology, 960th Hospital of the Chinese People's Liberation Army, Jinan, Shandong, People's Republic of China.
Liting ZhangDepartment of Stomatology, 960th Hospital of the Chinese People's Liberation Army, Jinan, Shandong, People's Republic of China.
Aiqin LvDepartment of Medical Services, Shandong University Stomatological Hospital, Jinan, Shandong, People's Republic of China.
Lu TangDepartment of Stomatology, 960th Hospital of the Chinese People's Liberation Army, Jinan, Shandong, People's Republic of China.ORCID 0009-0005-0897-1041

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Root canal treatment is common in dentistry. Pulp exposure and drainage during the procedure cause significant discomfort in children, triggering fear and anxiety that reduce their physical comfort and treatment compliance. Virtual reality (VR) glasses divert patients' attention from pain, alleviate anxiety, and feature simple operation and high safety. This study aims to investigate the safety and efficacy of virtual reality technology during pulp chamber open for drainage, providing empirical evidence for alleviating pain and reducing anxiety in pediatric patients undergoing the procedure. Methods: This study is designed as a single-center, randomized, controlled trial. This study will recruit 100 patients aged 6 to 12 years undergoing pulp chamber open for drainage. Participants will be randomly assigned to either the intervention or control group in a 1:1 ratio. Data collectors will be blinded to the study. The experimental group will receive conventional local anesthesia combined with VR glasses, while the control group will receive conventional local anesthesia alone. Assessments will be conducted at baseline collection (in the dental chair) (T0), during local anesthesia (T1), at pulp exposure (T2), and immediately after treatment completion (T3). Primary outcomes are pain scores (Wong-Baker FACES Pain Scale) and anxiety scores (Visual Analog Scale for Anxiety). Secondary outcomes include treatment compliance (Frankl Behavior Rating Scale), physiological parameters, adverse effects, and physician-patient satisfaction and acceptance. Trial Registration Number: ChiCTR2500111920.

Indexed as

anxietychildrenpainpulpitisroot canal treatmentvirtual reality

Identifiers

PMID42005584
PMCPMC13091592

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.