Evidence map›Paper›PMID 42005583›Full record

ArticleJournal of pain research2026

Modulation of Brain Activity in Patients with Acute Non-Specific Low Back Pain by Wentong Guan Therapy: A Functional Near-Infrared Spectroscopy Study.

Shifang Fu, Hao Chen, Xiaoyu Zhi, Fanqi Liu, Junfeng Zhang, Longsheng Ren, Mengying Rong, Yanguo Wang

Abstract read
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Article in Journal of pain research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Shifang Fu *Rehabilitation Department, Tianjin University of Traditional Chinese Medicine Second Affiliated Hospital, Tianjin, 300150, People's Republic of China.
Hao Chen *Acupuncture Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, People's Republic of China.
Xiaoyu ZhiRehabilitation Department, Tianjin University of Traditional Chinese Medicine Second Affiliated Hospital, Tianjin, 300150, People's Republic of China.
Fanqi LiuRehabilitation Department, Tianjin University of Traditional Chinese Medicine Second Affiliated Hospital, Tianjin, 300150, People's Republic of China.
Junfeng ZhangBrain Disease Department, Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, 300120, People's Republic of China.ORCID 0009-0007-5323-4264
Longsheng RenGraduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China.
Mengying RongGraduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, People's Republic of China.
Yanguo WangRehabilitation Department, Tianjin University of Traditional Chinese Medicine Second Affiliated Hospital, Tianjin, 300150, People's Republic of China.ORCID 0000-0002-1288-9324

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Wentong Guan Therapy (WTG) integrates techniques from Chinese massage, moxibustion, scraping, and cupping. Its analgesic mechanisms remain unclear. The brain functional network in patients with acute non-specific low back pain (ANSLBP) is impaired, and central nervous system regulation is one of the important mechanisms through which traditional Chinese medicine external therapies alleviate pain and functional impairment in ANSLBP. This study neurophysiologically evaluates WTG's pain modulation effect on the cerebral cortex in acute non-specific low back pain (ANSLBP). Methods: Twelve ANSLBP patients received a single WTG session. Subjective pain (Visual Analogue Scale, VAS), pressure pain threshold (PPT) using a force-measuring glove, and cortical hemodynamic changes via functional near-infrared spectroscopy (fNIRS) were assessed pre- and post-treatment. False discovery rate (FDR) corrected multiple comparisons. Results: Post-treatment, VAS scores significantly decreased (4.75±1.29 to 3.58±1.17, p<0.001) and PPT increased (77.29±39.83N to 94.58±39.79N, p<0.001). No significant brain network differences were found (P Conclusion: WTG effectively alleviates ANSLBP. The SAC and DLPFC are involved in WTG's neuromodulatory analgesic effects. Reduced ΔHbO

Indexed as

acute non-specific low back paindorsolateral prefrontal cortexfunctional near-infrared spectroscopyneuroactivitysomatosensory association cortexWentong Guan therapy

Identifiers

PMID42005583
PMCPMC13089269

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.