Evidence map›Paper›PMID 42005525›Full record

ArticleOrthopedic reviews2026

Use of Cryoneurolysis Therapy for the Management of Idiopathic Trigeminal Neuralgia.

Karina Gritsenko, Seung Mi Oh, Mukhlisa Zakirova, Nicole Rene Ortiz, Jagun Raghavan, Sarang Koushik, Omar Viswanath, Naum Shaparin

Abstract read
In one paragraph

Article in Orthopedic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karina GritsenkoAnesthesiology Montefiore Medical Center.
Seung Mi OhAnesthesiology Montefiore Medical Center.
Mukhlisa ZakirovaInternal Medicine Northwell Health.
Nicole Rene OrtizPhysical Medicine and Rehabilitation Montefiore Medical Center.
Jagun RaghavanThe Ohio State University.
Sarang KoushikAnesthesiology Mayo Clinic.
Omar ViswanathAnesthesiology Creighton University School of Medicine.
Naum ShaparinAnesthesiology Montefiore Medical Center.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Trigeminal neuralgia is a debilitating facial pain condition characterized by recurrent, electric shock-like episodes within the trigeminal nerve distribution. While first-line treatment involves pharmacologic therapy, treatment options are limited for patients who are refractory or poor surgical candidates. Case Presentation: We present a 75-year-old female with long-standing idiopathic trigeminal neuralgia refractory to combination anticonvulsant therapy and nerve block, with notable medication-related side effects. Management and Outcomes: The patient underwent percutaneous cryoneurolysis targeting the maxillary (V2) and mandibular (V3) divisions of the trigeminal nerve under fluoroscopic guidance. She experienced immediate pain reduction and complete symptom resolution at a one-month follow-up with no complications. Conclusion: This case highlights percutaneous cryoneurolysis as a minimally invasive treatment option for selected patients with refractory trigeminal neuralgia who are not candidates for open surgical intervention.

Indexed as

CryoneurolysisNeuropathic painTrigeminal neuralgia

Identifiers

PMID42005525
PMCPMC13082917

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.