Evidence map›Paper›PMID 42005350›Full record

ArticleInternational journal of pharmaceutics: X2026

Deep eutectic solvents based on matrine and menthol: A novel and safe transdermal penetration enhancer.

Hongdou He, Xinyu Huang, Yi Hong, Zhenpeng Qiu, Fei Xu, Shan Lu, Yujie Guo

Abstract read
In one paragraph

Article in International journal of pharmaceutics: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hongdou HeResearch Center for Pharmaceutical Preparations, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Xinyu HuangHubei Key Laboratory of Resources and Chemistry of Chinese Medicine, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Yi HongResearch Center for Pharmaceutical Preparations, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Zhenpeng QiuHubei Shizhen Laboratory, Wuhan 430061, China.
Fei XuInstitute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Shan LuResearch Center for Pharmaceutical Preparations, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Yujie GuoResearch Center for Pharmaceutical Preparations, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transdermal drug delivery has attracted extensive attention due to its ability to bypass the first-pass metabolism, maintain plasma drug concentrations, and improve patient compliance. However, the transdermal delivery of hydrophilic drugs is still quite challenging. This study aims to develop a novel deep eutectic solvent (DES) composed of matrine (MT) from

Indexed as

Deep eutectic solventsMatrineMentholMolecular mechanismTheoretical calculationsTransdermal delivery

Identifiers

PMID42005350
PMCPMC13090524

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.