Evidence map›Paper›PMID 42005334›Full record

ArticleFood science & nutrition2026

Antidiabetic Activity of Phenolic-Rich Extracts From

Aziz Zouhri, Naoual El Menyiy, Yahya El-Mernissi, Rafik El-Mernissi, Mohamed Reda Kachmar, Farhan Siddique, Rabie Kachkoul, Sumaira Nadeem, El Mouhri Ghita, Naima Mammate and 5 more

Abstract read
In one paragraph

Article in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Aziz ZouhriBioactives and Environmental Health Laboratory, Faculty of Sciences Moulay Ismail University Meknes Morocco.ORCID https://orcid.org/0009-0004-9546-8577
Naoual El MenyiyLaboratory of Pharmacology National Agency for Medicinal and Aromatic Plants Taounate Morocco.ORCID https://orcid.org/0000-0002-4842-2056
Yahya El-MernissiResearch Unit in Applied Chemistry, Faculty of Science and Techniques Abdelmalek Essaadi University Al Hoceima Morocco.ORCID https://orcid.org/0000-0001-5807-8175
Rafik El-MernissiBioactives and Environmental Health Laboratory, Faculty of Sciences Moulay Ismail University Meknes Morocco.
Mohamed Reda KachmarHigh Institute of Nursing Professions and Health Techniques Béni Mellal Morocco.ORCID https://orcid.org/0000-0001-8191-1129
Farhan SiddiqueSchool of Pharmaceutical Science and Technology Tianjin University Tianjin P. R. China.
Rabie KachkoulFaculty of Medicine and Pharmacy, Laboratory of Biochemistry Sidi Mohammed Ben Abdellah University Fez Morocco.ORCID https://orcid.org/0000-0003-1755-9882
Sumaira NadeemDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy Bahauddin Zakariya University Multan Pakistan.
El Mouhri GhitaFaculty of Medicine and Pharmacy, Laboratory of Biochemistry Sidi Mohammed Ben Abdellah University Fez Morocco.
Naima MammateLaboratory of Epidemiology and Research in Health Sciences, Faculty of Medicine, Pharmacy, and Dental Medicine Sidi Mohammed Ben Abdellah University of Fez Fez Morocco.ORCID https://orcid.org/0000-0003-0477-7709
Yousef A Bin JardanDepartment of Pharmaceutics, College of Pharmacy King Saud University Riyadh Saudi Arabia.
Esmael M AlyamiDepartment of Biology, College of Science King Khalid University Abha Asir Saudi Arabia.
Mohammed DauelbaitUniversity of Juba Juba South Sudan.ORCID https://orcid.org/0009-0005-1340-4420
Mohammad KhalidDepartment of Pharmaceutics, College of Pharmacy King Khalid University Abha Asir Saudi Arabia.
Lhoussain HajjiBioactives and Environmental Health Laboratory, Faculty of Sciences Moulay Ismail University Meknes Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes, a prevalent metabolic disorder, has prompted extensive research into natural remedies with hypoglycemic potential and minimal side effects. The aim of this study was to examine phenolic compounds using high-performance liquid chromatography (HPLC). Acute toxicity was assessed in mice following OECD 423 criteria, and anti-diabetic potential was tested by intraperitoneal injection of alloxan (150 mg/kg) to induce experimental diabetes. Acute toxicity assessment found no adverse effects, while chemical analysis revealed various phenolic compounds like rutin, quercetin, and gallic acid, known for their therapeutic properties. In vitro experiments with the aqueous extract showed significant inhibition of pancreatic

Indexed as

antidiabetic activityCistus albidusglibenclamideα‐amylase alloxan

Identifiers

PMID42005334
PMCPMC13088270

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.